Below are current clinical trials.1 studies in Mouth cancer
(open studies only).
Filter this list of studies by location, status and more.
A Study to Compare the Toxic Effects and Disease Outcomes of Intensity-Modulated Proton Beam Therapy versus Intensity-Modulated Photon Therapy for the Treatment of Mouth and Throat Cancers
Study type: Interventional What is this?
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study phase: II/III What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.
About this study
The purpose of this study is to compare the toxic side effects and disease outcomes of intensity modulated photon therapy versus intensity modulated proton therapy. Participants may also receive chemotherapy along with radiation therapy.
Participating Mayo Clinic locations
Study statuses change often. Please contact us for help.
Print study details
- Rochester, Minnesota: 16-004913
NCT ID: NCT01893307
Sponsor Protocol Number: 2012-0825
Oct. 21, 2016
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- Head and neck cancers. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed Oct. 26, 2015.
- What you need to know about oral cancer. National Cancer Institute. http://www.cancer.gov/publications/patient-education/wyntk-oral-cancer. Accessed Oct. 26, 2015.
- Lip and oral cavity cancer treatment (PDQ). National Cancer Institute. http://www.cancer.gov/types/head-and-neck/hp/lip-mouth-treatment-pdq. Accessed Oct. 26, 2015.
- The oral cancer exam. National Institute of Dental and Craniofacial Research. http://www.nidcr.nih.gov/OralHealth/Topics/OralCancer/TheOralCancerExam.htm. Accessed Oct. 26, 2015.
- Cancer-related fatigue. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed Oct. 26, 2015.
- Erbitux (prescribing information). Branchburg, N.J.: Eli Lilly and Company; 2015. http://www.erbitux.com. Accessed Oct. 27, 2015.
- AskMayoExpert. Head and neck cancers. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2015.
- Cook AJ. Allscripts EPSi. Mayo Clinic, Rochester, Minn. March 30, 2016.
- Van Abel, KM. (expert opinion). Mayo Clinic, Rochester, Minn. June 14, 2016.