Overview

Sheehan's syndrome is a condition that affects women who lose a life-threatening amount of blood in childbirth or who have severe low blood pressure during or after childbirth, which can deprive the body of oxygen. In Sheehan's syndrome, the lack of oxygen can damage your pituitary gland.

Sheehan's syndrome causes the pituitary gland to not produce enough pituitary hormones (hypopituitarism). Also called postpartum hypopituitarism, Sheehan's syndrome is rare in industrialized nations, largely due to improved obstetrical care. But it's a major threat to women in developing countries.

Treatment of Sheehan's syndrome involves lifelong hormone replacement therapy.

Nov. 22, 2016
References
  1. DeCherney AH, et al. Thyroid & other endocrine disorders during pregnancy. In: Current Diagnosis & Treatment Obstetrics & Gynecology. 11th ed. New York, N.Y.: The McGraw-Hill Companies; 2013. http://www.accessmedicine.com. Accessed Oct. 2, 2016.
  2. Pituitary gland. Hormone Health Network. http://www.hormone.org/hormones-and-health/endocrine-glands-and-types-of-hormones/pituitary-gland. Accessed Oct. 2, 2016.
  3. Ferri FF. Sheehan syndrome. In: Ferri's Clinical Advisor 2017. Philadelphia, Pa.: Elsevier; 2017. https://www.clinicalkey.com. Accessed Oct. 2, 2016.
  4. Sheehan syndrome. Genetic and Rare Diseases Information Center. https://rarediseases.info.nih.gov/diseases/7630/sheehan-syndrome. Accessed Oct. 1, 2016.
  5. Snyder PJ. Treatment of hypopituitarism. http://www.uptodate.com/home. Accessed Oct. 1, 2016.
  6. Belfort MA. Overview of postpartum hemorrhage. http://www.uptodate.com/home. Accessed Oct. 1, 2016.
  7. Snyder PJ. Causes of hypopituitarism. http://www.uptodate.com/home. Accessed Oct. 1, 2016.
  8. DeCherney AH, et al. Thyroid & other endocrine disorders during pregnancy. In: Current Diagnosis & Treatment Obstetrics & Gynecology. 11th ed. New York, N.Y.: The McGraw-Hill Companies; 2013. http://www.accessmedicine.com. Accessed Oct. 2, 2016.
  9. Pituitary gland. Hormone Health Network. http://www.hormone.org/hormones-and-health/endocrine-glands-and-types-of-hormones/pituitary-gland. Accessed Oct. 2, 2016.
  10. Ferri FF. Sheehan syndrome. In: Ferri's Clinical Advisor 2017. Philadelphia, Pa.: Elsevier; 2017. https://www.clinicalkey.com. Accessed Oct. 2, 2016.
  11. Sheehan syndrome. Genetic and Rare Diseases Information Center. https://rarediseases.info.nih.gov/diseases/7630/sheehan-syndrome. Accessed Oct. 1, 2016.
  12. Snyder PJ. Treatment of hypopituitarism. http://www.uptodate.com/home. Accessed Oct. 1, 2016.
  13. Belfort MA. Overview of postpartum hemorrhage. http://www.uptodate.com/home. Accessed Oct. 1, 2016.
  14. Snyder PJ. Causes of hypopituitarism. http://www.uptodate.com/home. Accessed Oct. 1, 2016.