Before Using

Drug information provided by: Merative, Micromedex®

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of propranolol capsules, extended-release capsules, and tablets in the pediatric population. Safety and efficacy have not been established.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of propranolol oral solution in children.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of propranolol oral solution to treat proliferating infantile hemangioma in children 5 weeks to 5 months of age. However, safety and efficacy have not been established in children older than 1 year of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of propranolol in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving propranolol.

No information is available on the relationship of age to the effects of propranolol oral solution in geriatric patients.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Rizatriptan
  • Thioridazine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Abametapir
  • Albuterol
  • Bupivacaine
  • Bupivacaine Liposome
  • Bupropion
  • Capmatinib
  • Ceritinib
  • Clonidine
  • Crizotinib
  • Darunavir
  • Desvenlafaxine
  • Diatrizoate
  • Diltiazem
  • Dronedarone
  • Epinephrine
  • Escitalopram
  • Eslicarbazepine Acetate
  • Fedratinib
  • Fenoldopam
  • Fexinidazole
  • Fingolimod
  • Fluoxetine
  • Formoterol
  • Haloperidol
  • Indacaterol
  • Iobenguane I 131
  • Iohexol
  • Lacosamide
  • Lercanidipine
  • Levalbuterol
  • Lidocaine
  • Mefloquine
  • Mepivacaine
  • Olodaterol
  • Oxymetazoline
  • Pixantrone
  • Ponesimod
  • Prilocaine
  • Rivastigmine
  • Salmeterol
  • Simeprevir
  • Siponimod
  • Sparsentan
  • Terbutaline
  • Venlafaxine
  • Verapamil
  • Vilanterol
  • Zileuton

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acarbose
  • Aceclofenac
  • Acemetacin
  • Acetyldigoxin
  • Albiglutide
  • Alfuzosin
  • Alogliptin
  • Aluminum Carbonate, Basic
  • Aluminum Hydroxide
  • Aluminum Phosphate
  • Amtolmetin Guacil
  • Aspirin
  • Bromfenac
  • Bufexamac
  • Bunazosin
  • Calcium Carbonate
  • Canagliflozin
  • Celecoxib
  • Chlorpromazine
  • Chlorpropamide
  • Cholestyramine
  • Choline Salicylate
  • Cimetidine
  • Clonixin
  • Dapagliflozin
  • Deslanoside
  • Dexibuprofen
  • Dexketoprofen
  • Diclofenac
  • Diflunisal
  • Digitoxin
  • Digoxin
  • Dihydroergotamine
  • Dihydroxyaluminum Aminoacetate
  • Dihydroxyaluminum Sodium Carbonate
  • Dipyrone
  • Doxazosin
  • Droxicam
  • Dulaglutide
  • Empagliflozin
  • Ergotamine
  • Ertugliflozin
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Exenatide
  • Felbinac
  • Fenoprofen
  • Fepradinol
  • Feprazone
  • Flecainide
  • Floctafenine
  • Flufenamic Acid
  • Flurbiprofen
  • Fluvoxamine
  • Glimepiride
  • Glipizide
  • Glyburide
  • Ibuprofen
  • Indomethacin
  • Insulin Aspart, Recombinant
  • Insulin Degludec
  • Insulin Detemir
  • Insulin Glargine, Recombinant
  • Insulin Glulisine
  • Insulin Human Inhaled
  • Insulin Human Isophane (NPH)
  • Insulin Human Regular
  • Insulin Lispro, Recombinant
  • Ketoprofen
  • Ketorolac
  • Linagliptin
  • Liraglutide
  • Lixisenatide
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Magaldrate
  • Meclofenamate
  • Mefenamic Acid
  • Meloxicam
  • Metformin
  • Metildigoxin
  • Miglitol
  • Morniflumate
  • Moxisylyte
  • Nabumetone
  • Naproxen
  • Nateglinide
  • Nepafenac
  • Niflumic Acid
  • Nimesulide
  • Nimesulide Beta Cyclodextrin
  • Oxaprozin
  • Oxyphenbutazone
  • Parecoxib
  • Phenoxybenzamine
  • Phentolamine
  • Phenylbutazone
  • Piketoprofen
  • Pioglitazone
  • Piroxicam
  • Pramlintide
  • Pranoprofen
  • Prazosin
  • Proglumetacin
  • Propyphenazone
  • Proquazone
  • Quinidine
  • Repaglinide
  • Rifapentine
  • Rofecoxib
  • Rosiglitazone
  • Salicylic Acid
  • Salsalate
  • Saxagliptin
  • Sitagliptin
  • Sodium Salicylate
  • St John's Wort
  • Sulindac
  • Tamsulosin
  • Tenoxicam
  • Terazosin
  • Tiaprofenic Acid
  • Tolazamide
  • Tolbutamide
  • Tolfenamic Acid
  • Tolmetin
  • Trimazosin
  • Urapidil
  • Valdecoxib
  • Vildagliptin

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Tobacco

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Anaphylactic reaction (severe), history of—May increase risk for repeated anaphylactic reactions.
  • Angina (severe chest pain) or
  • Glaucoma or
  • Heart attack, recent or
  • Muscle problems (eg, myopathy, myotonia)—Use with caution. May make these conditions worse.
  • Asthma or
  • Bradycardia (slow heartbeat), without a pacemaker or
  • Cardiogenic shock (shock caused by heart attack) or
  • Heart block, without a pacemaker or
  • Heart failure, decompensated or
  • Sick sinus syndrome (type of abnormal heart rhythm), without a pacemaker or
  • Tremors due to Parkinson's disease—Should not be used in patients with these conditions.
  • Asthma, or history of or
  • Bradycardia (slow heartbeat), severe or
  • Bronchospasm, history of or
  • Hypotension (low blood pressure) or
  • Infants weighing less than 2 kilograms or
  • Pheochromocytoma (an adrenal problem) or
  • Premature infants with corrected age younger than 5 weeks of age—Hemangeol® should not be given to patients with these conditions.
  • Colds or
  • Infection or
  • Poor oral food intake (eg, not eating, vomiting) or
  • Stress—Hemangeol® may increase the risk of low blood sugar in patients with these conditions.
  • Diabetes or
  • Hyperthyroidism (overactive thyroid) or
  • Hypoglycemia (low blood sugar)—May cover up some of the signs and symptoms of these diseases, such as a fast heartbeat.
  • Kidney disease or
  • Liver disease—Use with caution. The effects may be increased because of slower removal from the body.
  • Lung disease (eg, bronchitis, emphysema)—Use with caution. May cause difficulty with breathing in patients with this condition.
  • Patients who are fasting (eg, surgery, not eating regularly, vomiting)—May increase risk of hypoglycemia (low blood sugar).
  • Tachycardia (fast heartbeat) or
  • Wolff-Parkinson-White syndrome (rare heart condition)—May cause very slow heartbeat in patients with these conditions.

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Portions of this document last updated: Feb. 01, 2024

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