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Causes
By Mayo Clinic staff
The cause of adenomyosis isn't known. Some experts believe that adenomyosis results from the direct invasion of endometrial cells into the uterine walls. Sometimes an operation, such as a Caesarean section (C-section), can make this invasion of cells easier. Other experts speculate that adenomyosis originates within the uterine walls (myometrium) from endometrial tissue deposited there when the uterus was first forming in the female fetus.
Another theory suggests a link between adenomyosis and childbirth — that an inflammation of the uterine lining (endometritis) during the postpartum period might cause a break in the normal boundary of the cells of the uterus. Regardless of how adenomyosis develops, its growth depends on the circulating estrogen in a woman's body. When estrogen disappears at menopause, adenomyosis resolves.
