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Treatments and drugs

By Mayo Clinic staff

Adenomyosis usually goes away after menopause, so treatment may depend on how close you are to that stage of life.

Treatment options for adenomyosis include:

  • Anti-inflammatory drugs. If you're nearing menopause, your doctor may have you try anti-inflammatory medications, such as ibuprofen (Advil, Motrin, others), to control the pain. By starting an anti-inflammatory medicine two to three days before your period begins and continuing to take it during your period, you can reduce menstrual blood flow in addition to relieving pain.
  • Hormone medications. Controlling your menstrual cycle through combined estrogen-progestin oral contraceptives or through hormone-containing patches or vaginal rings may lessen the heavy bleeding and pain associated with adenomyosis. Progestin-only contraception, such as an intrauterine device containing progestin or a continuous-use birth control pill, often leads to amenorrhea — the absence of your menstrual periods — which may provide relief.
  • Hysterectomy. If your pain is severe and menopause is years away, your doctor may suggest surgery to remove your uterus (hysterectomy). Removing your ovaries isn't necessary to control adenomyosis.
References
  1. Stewart EA. Adenomyosis. http://www.uptodate.com/home/index.html. Accessed Jan. 8, 2010.
  2. Schuiling KD, et al. Benign gynecologic conditions. In: Schuiling KD, et al. Women's Gynecologic Health. Sudbury, Mass.: Jones and Bartlett; 2006:577.
  3. Drinville JS, et al. Benign disorders of the uterine corpus. In: DeCherney AH, et al. Current Diagnosis & Treatment Obstetrics & Gynecology. 10th ed. New York, N.Y.: McGraw-Hill Medical; 2007. http://www.accessmedicine.com/content.aspx?aid=2389400. Accessed Jan. 8, 2010.
  4. Katz VL. Benign gynecologic lesions: Vulva, vagina, cervix, uterus, oviduct, ovary. In: Katz VL, et al. Comprehensive Gynecology. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2007. http://www.mdconsult.com/das/book/body/178499985-2/0/1524/120.html?tocnode=53759294&fromURL=120.html. Accessed Jan. 12, 2010.
  5. Dysmenorrhea. The Merck Manuals: Home Edition for Patients and Caregivers. http://www.merck.com/mmhe/sec22/ch244/ch244c.html#sec22-ch244-ch244c-211. Accessed Jan. 12, 2010.
  6. Meredith SM, et al. Diagnostic accuracy of transvaginal sonography for the diagnosis of adenomyosis: Systematic review and metaanalysis. American Journal of Obstetrics & Gynecology. 2009;201:107.e1.
  7. Hesla JS, et al. Endometriosis. In: Rock JA, et al. Te Linde's Operative Gynecology. 10th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins; 2008:438.
  8. Panganamamula UR, et al. Is prior uterine surgery a risk factor for adenomyosis? Obstetrics & Gynecology. 2004;104:1034.
DS00636 Feb. 20, 2010

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