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- Obesity
- Obesity, childhood (See: Childhood obesity)
- Obsessive-compulsive disorder
- Obsessive-compulsive personality disorder (See: Personality disorders)
- Obstetric cholestasis (See: Cholestasis of pregnancy)
- Obstructive sleep apnea (See: Sleep apnea, obstructive)
- Occupational asthma
- OCD (See: Obsessive-compulsive disorder)
- Ocular albinism (See: Albinism)
- Ocular melanoma (See: Eye melanoma)
- Ocular migraine
- Ocular rosacea
- Oculocutaneous albinism (See: Albinism)
- ODD (See: Oppositional defiant disorder (ODD))
- OHSS (See: Ovarian hyperstimulation syndrome)
- Oligohydramnios
- Onychomycosis (See: Nail fungus)
- Oppositional defiant disorder (ODD)
- Optic neuritis
- Oral cancer (See: Mouth cancer)
- Oral candidiasis (See: Oral thrush)
- Oral lichen planus
- Oral thrush
- Orchitis
- Orophayrngeal cancer (See: Throat cancer)
- Orthostatic hypotension (See: Orthostatic hypotension (postural hypotension))
- Orthostatic hypotension (postural hypotension)
- Osgood-Schlatter disease
- Osteoarthritis
- Osteoarthritis, cervical (See: Cervical spondylosis)
- Osteochondritis dissecans
- Osteomalacia
- Osteomyelitis
- Osteonecrosis (See: Avascular necrosis)
- Osteophytes (See: Bone spurs)
- Osteoporosis
- Otitis externa (See: Swimmer's ear)
- Otitis media (See: Ear infection (middle ear))
- Outer ear infection (See: Swimmer's ear)
- Ovarian cancer
- Ovarian cysts
- Ovarian hyperstimulation syndrome
- Overactive bladder
- Overactive thyroid (See: Hyperthyroidism)
- Oxyphil cell carcinoma (See: Hurthle cell cancer)
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