SymptomsBy Mayo Clinic staff
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Skin changes are the only signs of acanthosis nigricans. You'll notice dark, thickened, velvety skin in body folds and creases — typically in your armpits, groin and neck. The skin changes appear slowly, sometimes over months or years. The affected skin may also smell bad or itch.
When to see a doctor
Consult your doctor if you notice changes in your skin — especially if the changes appear suddenly. You may have an underlying condition that needs treatment.
- Habif TP. Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 5th ed. Edinburgh, U.K.; New York, N.Y.: Mosby Elsevier; 2010. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-7234-3541-9..X0001-6--TOP&isbn=978-0-7234-3541-9&uniqId=230100505-57. Accessed March 29, 2012.
- Goldstein BG, et al. Metabolic and inherited diseases affecting the skin. http://www.uptodate.com/index.html. Accessed March 29, 2012.
- Rose PT. Pigmentary disorders. Medical Clinics of North America. 2009;93:1225.
- Owen C. Cutaneous manifestations of internal malignancy. http://www.uptodate.com/index. Accessed March 30, 2012.