Tests and diagnosis
By Mayo Clinic staffAcanthosis nigricans is typically detected during a skin exam. Rarely, a small skin sample is removed (biopsied) for examination in a lab.
If the cause of acanthosis nigricans is unclear, your doctor may recommend blood tests, X-rays or other tests to look for possible underlying causes.
- DeWitt CA, et al. Cutaneous manifestations of internal malignant disease: Cutaneous paraneoplastic syndromes. In: Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, N.Y.: The McGraw Hill Companies; 2008. http://www.accessmedicine.com/content.aspx?aID=2961164. Accessed Jan. 10, 2010.
- Goldstein BG, et al. Metabolic and inherited diseases affecting the skin. http://www.uptodate.com/home/index.html. Accessed Jan. 9, 2010.
- Cutaneous manifestations of internal disease. In: Habif TP. Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 5th ed. Philadelphia, Pa.: Elsevier; 2010. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-0-7234-3541-9..00035-3--s0160&displayedEid=4-u1.0-B978-0-7234-3541-9..00035-3--s0180&uniq=178031830&isbn=978-0-7234-3541-9&sid=938193257#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-0-7234-3541-9..00035-3--st0155%3Bfrom%3Dcontent%3Bisbn%3D978-0-7234-3541-9%3Btype%3DbookPage. Accessed Jan.10, 2010.
- Reynolds RV. Cutaneous manifestations of internal malignancy. http://www.uptodate.com/home/index.html. Accessed Jan. 9, 2010.
- Acanthosis nigricans. American Osteopathic College of Dermatology. www.aocd.org/skin/dermatologic_diseases/acanthosis_nigrica.html. Accessed Jan. 10, 2010

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