Mayo Clinic Health Manager

Get free personalized health guidance for you and your family.

Get Started

Free

E-Newsletter

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Symptoms

By Mayo Clinic staff

CLICK TO ENLARGE

Illustration showing person with acromegaly Person with acromegaly

One of the most common signs of acromegaly is enlarged hands and feet. People with this disorder often notice that they can no longer put on rings that used to fit and that their shoe size has progressively increased.

Acromegaly may also cause you to experience gradual changes in the shape of your face, such as a protruding lower jaw and brow, an enlarged nose, thickened lips, and wider spacing between your teeth.

Because acromegaly tends to progress slowly, early signs may not be readily apparent for several years. Sometimes, people notice the condition only by comparing old photographs.

Acromegaly may produce the following signs and symptoms, which can vary from one person to another:

  • Enlarged hands and feet
  • Coarsened, enlarged facial features
  • Coarse, oily, thickened skin
  • Excessive sweating and body odor
  • Small outgrowths of skin tissue (skin tags)
  • Fatigue and muscle weakness
  • A deepened, husky voice due to enlarged vocal cords and sinuses
  • Severe snoring due to obstruction of the upper airway
  • Impaired vision
  • Headaches
  • Enlarged tongue
  • Pain and limited joint mobility
  • Menstrual cycle irregularities in women
  • Erectile dysfunction in men
  • Enlarged liver, heart, kidneys, spleen and other organs
  • Increased chest size (barrel chest)

When to see a doctor
If you have signs and symptoms associated with acromegaly, contact your doctor for an evaluation.

Acromegaly usually develops slowly, and even your family members may not initially notice the gradual physical changes that occur with this disorder. Early diagnosis is important, however, so that you can receive proper care. Acromegaly can lead to serious complications if it's not treated.

DS00478

Aug. 2, 2008

© 1998-2009 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Reliable tools for healthier lives," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Text Size: smaller largerlarger