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Risk factors
By Mayo Clinic staffFactors that may increase the risk of acute lymphocytic leukemia include:
- Previous cancer treatment. Children and adults who've had certain types of chemotherapy and radiation therapy for other kinds of cancer may have an increased risk of developing acute lymphocytic leukemia.
- Exposure to radiation. People exposed to very high levels of radiation, such as survivors of a nuclear reactor accident, have an increased risk of developing acute lymphocytic leukemia.
- Genetic disorders. Certain genetic disorders, such as Down syndrome, are associated with some increased risk of acute lymphocytic leukemia.
- Having a brother or sister with ALL. People who have a sibling, including a twin, with acute lymphocytic leukemia have an increased risk of ALL.
References
- Rabin KR, et al. Clinical manifestations of acute lymphoblastic leukemia. In: Hoffman R, et al. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa.: Churchill Livingstone; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-443-06715-0..X5001-8--TOP&isbn=978-0-443-06715-0&uniq=210978719. Accessed Aug. 16, 2010.
- Hoelzer D, et al. Acute lymphocytic leukemia in adults. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2007:2191.
- Pieters R, et al. Biology and treatment of acute lymphoblastic leukemia. Hematology and Oncology Clinics of North America. 2010;24:1.
- Acute lymphocytic leukemia. The Leukemia & Lymphoma Society. http://www.leukemia-lymphoma.org/all_page?item_id=7049. Accessed Aug. 16, 2010.
- Integrative medicine and complementary and alternative therapies as part of blood cancer care. The Leukemia & Lymphoma Society. http://www.leukemia-lymphoma.org/attachments/National/br_1150734030.pdf. Accessed Aug. 16, 2010.
- Faderl S, et al. Adult acute lymphoblastic leukemia. Cancer. 2010;116:1165.
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