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Causes

By Mayo Clinic staff

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Illustration showing normal and infected sinuses 
Sinusitis

When you have sinusitis, the mucous membranes of your nose, sinuses and throat (upper respiratory tract) become inflamed. Swelling obstructs the sinus openings and prevents mucus from draining normally, causing facial pain and other sinusitis symptoms.

Blocked sinuses create a moist environment that makes it easier for infection to take hold. Sinuses that become infected and can't drain become pus filled, leading to signs and symptoms such as thick, yellow or greenish discharge and other symptoms of infection.

Acute sinusitis can be caused by:

  • Viral infection. Most cases of acute sinusitis are caused by the common cold.
  • Bacterial infection. When an upper respiratory tract infection persists longer than seven to 10 days, it's more likely to be caused by a bacterial infection than by a viral infection.
  • Fungal infection. You're at increased risk of a fungal infection if you have sinus abnormalities or a weakened immune system.

Some health conditions can increase your risk of getting a sinus infection that causes sinusitis, or can increase your risk of getting sinusitis that isn't caused by an underlying infection. These conditions include:

  • Allergies such as hay fever. Inflammation that occurs with allergies may block your sinuses.
  • Nasal polyps or tumors. These tissue growths may block the nasal passages or sinuses.
  • Deviated nasal septum. A crooked septum — the wall between the nostrils — may restrict or block sinus passages.
  • Tooth infection. A small number of cases of acute sinusitis are caused by an infected tooth.
  • Other medical conditions. The complications of cystic fibrosis, gastroesophageal reflux disease (GERD) or immune system disorders may result in blocked sinuses or an increased risk of infection.
References
  1. Sinuses|Sinusitius|Rhinosinusitis. American Academy of Allergy, Asthma & Immunology. http://www.aaaai.org/conditions-and-treatments/conditions-a-to-z-search/sinuses,-sinusitis,-rhinosinusitis.aspx. Accessed March 25, 2013.
  2. Lalwani AK. Current Diagnosis & Treatment in Otolaryngology-Head & Neck Surgery. 3rd ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=39. Accessed March 25, 2013.
  3. Fact sheet: 20 questions about your sinuses. American Academy of Otolaryngology-Head and Neck Surgery. http://www.entnet.org/HealthInformation/sinuses.cfm. Accessed March 31, 2013.
  4. Aring AM, et al. Acute rhinosinusitis in adults. American Family Physician. 2011;83:1057.
  5. Primary amebic meningoencephalitis (PAM): Prevention & control. Centers for Disease Control and Prevention. http://www.cdc.gov/parasites/naegleria/prevention.html. Accessed March 24, 2013.
  6. Meltzer EO, et al. Rhiosinusitis diagnosis and management for the clinician: A synopsis of recent consensus guidelines. Mayo Clinic Proceedings. 2011;86:427.
  7. Hayward G, et al. Intranasal corticosteroids in management of acute sinusitis: A systematic review and meta-analysis. Annals of Family Medicine. 2012;10:241.
  8. Leung RS, et al. The diagnosis and management of acute and chronic sinusitis. Primary Care: Clinics in Office Practice. 2008;35:11.
  9. Sinupret+. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed April 1, 2013.
  10. SinuGuard. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed April 1, 2013.
DS00170 July 2, 2013

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