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Definition

By Mayo Clinic staff

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Illustration showing normal uterus vs. uterus with adenomyosis
Adenomyosis

Adenomyosis (ad-uh-no-my-O-sis) is a condition in which endometrial tissue, which normally lines the uterus, is present within and grows into the muscular walls of the uterus. This is most likely to happen late in your childbearing years and after you've had children.

Adenomyosis isn't the same as endometriosis — a condition in which the uterine lining becomes implanted outside the uterus — although women with adenomyosis often also have endometriosis. The cause of adenomyosis remains unknown, but the disease typically disappears after menopause. For women who experience severe discomfort from adenomyosis, there are treatments that can help, but hysterectomy is the only cure.

Although adenomyosis can be quite painful, the condition is generally harmless.

References
  1. Stewart EA. Adenomyosis. http://www.uptodate.com/home/index.html. Accessed Jan. 8, 2010.
  2. Schuiling KD, et al. Benign gynecologic conditions. In: Schuiling KD, et al. Women's Gynecologic Health. Sudbury, Mass.: Jones and Bartlett; 2006:577.
  3. Drinville JS, et al. Benign disorders of the uterine corpus. In: DeCherney AH, et al. Current Diagnosis & Treatment Obstetrics & Gynecology. 10th ed. New York, N.Y.: McGraw-Hill Medical; 2007. http://www.accessmedicine.com/content.aspx?aid=2389400. Accessed Jan. 8, 2010.
  4. Katz VL. Benign gynecologic lesions: Vulva, vagina, cervix, uterus, oviduct, ovary. In: Katz VL, et al. Comprehensive Gynecology. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2007. http://www.mdconsult.com/das/book/body/178499985-2/0/1524/120.html?tocnode=53759294&fromURL=120.html. Accessed Jan. 12, 2010.
  5. Dysmenorrhea. The Merck Manuals: Home Edition for Patients and Caregivers. http://www.merck.com/mmhe/sec22/ch244/ch244c.html#sec22-ch244-ch244c-211. Accessed Jan. 12, 2010.
  6. Meredith SM, et al. Diagnostic accuracy of transvaginal sonography for the diagnosis of adenomyosis: Systematic review and metaanalysis. American Journal of Obstetrics & Gynecology. 2009;201:107.e1.
  7. Hesla JS, et al. Endometriosis. In: Rock JA, et al. Te Linde's Operative Gynecology. 10th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins; 2008:438.
  8. Panganamamula UR, et al. Is prior uterine surgery a risk factor for adenomyosis? Obstetrics & Gynecology. 2004;104:1034.
DS00636 Feb. 20, 2010

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