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Lifestyle and home remedies
By Mayo Clinic staffMany fade creams and lotions are available in department stores, in drugstores and on the Internet to lighten age spots and other skin discoloration. These may be good options depending on the darkness of the age spot and how often you apply the cream. Successful treatment needs to penetrate through the base of the epidermis — the topmost layer of skin — where the extra pigment is located. This means regular use over several weeks or months may be necessary before any noticeable results occur.
If you do opt for an over-the-counter (nonprescription) fade cream, choose one that contains hydroquinone, deoxyarbutin, glycolic acid or kojic acid. Note that some products, especially those that contain hydroquinone, may cause skin irritation after prolonged use.
- Schaffer JV, et al. Benign pigmented skin lesions other than melanocytic nevi (moles). http://www.uptodate.com/home/index.html. Accessed Dec. 3, 2008.
- Ortonne JP, et al. Treatment of solar lentigines. Journal of the American Academy of Dermatology. 2006;54:S262.
- Farris PK. Combination therapy for solar lentigines. Journal of Drugs in Dermatology. 2004;3:S23.
- What you need to know about moles and dysplastic nevi. National Cancer Institute. http://www.cancer.gov/pdf/WYNTK/WYNTK_moles.pdf. Accessed Dec. 4, 2008.
- The sun and your skin. American Academy of Dermatology. http://www.aad.org/public/publications/pamphlets/sun_sun.html. Accessed Dec. 3, 2008.
- Habif TP. Light-related diseases and disorders of pigmentation. In: Habif TP. Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 4th ed. Philadelphia, Pa.: Mosby; 2004. http://www.mdconsult.com/das/book/body/112580021-4/0/1195/130.html?tocnode=51442208&fromURL=130.html#4-u1.0-B0-323-01319-8..50021-2--cesec13_2361. Accessed Dec. 4, 2008.
- Alpha hydroxy acids. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Dec. 4, 2008.
- Draelos ZD. Skin lightening preparations and the hydroquinone controversy. Dermatologic Therapy. 2007;20:308.
- Chawla S, et al. Mechanism of tyrosinase inhibition by deoxyArbutin and its second-generation derivatives. British Journal of Dermatology. 2008;159:1267.
