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Age spots (liver spots)By Mayo Clinic staff
Original Article: http://www.mayoclinic.com/health/age-spots/DS00912
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|Age spots on the shoulder and back|
Age spots — also called liver spots and solar lentigines — are flat gray, brown or black spots. They vary in size and usually appear on the face, hands, shoulders and arms — areas most exposed to the sun. Though age spots are very common in adults older than age 40, they can affect younger people as well.
True age spots are harmless and don't need treatment, but they can look like cancerous growths. For cosmetic reasons, age spots can be lightened with skin-bleaching products or removed. However, preventing age spots — by avoiding the sun and using sunscreen — may be the easiest way to maintain your skin's youthful appearance and to avoid these dark skin spots.
Age spots typically develop in people with a fair complexion, but they can be seen in those with darker skin. Age spots:
- Are flat, oval areas of increased pigmentation
- Are usually brown, black or gray
- Occur on skin that has had the most sun exposure over the years, such as the backs of hands, tops of feet, face, shoulders and upper back
Age spots range from freckle-size to more than a half inch (1 centimeter) across and can group together, making them more prominent.
When to see a doctor
You may not like the way they look, but age spots are usually harmless and don't require medical care. However, your doctor should evaluate spots that are dark or have changed in appearance, because these changes can be signs of melanoma, a serious form of skin cancer.
It's best to have any new skin changes evaluated by a doctor, especially if a spot or lesion:
- Is darkly pigmented
- Is rapidly increasing in size
- Has an irregular border
- Has an unusual combination of colors
- Is accompanied by itching, redness, tenderness or bleeding
Age spots are caused primarily by years of exposure to ultraviolet (UV) light from the sun. The use of commercial tanning lamps and tanning beds can also contribute to the development of age spots.
The pigment in the upper layer of skin (epidermis) that gives your skin its normal color is called melanin. UV light accelerates the production of melanin, creating a tan that helps protect deeper layers of skin from UV rays.
On areas of the skin that have years of frequent and prolonged sun exposure, age spots appear when melanin becomes "clumped" or is produced in particularly high concentrations. In addition to sun exposure, simply becoming older can cause the extra production of melanin.
Your genetic makeup may also play a role in how susceptible you are to the development of age spots.
Although anyone can develop age spots, you may be more likely to develop the condition if you:
- Have light-colored or fair skin
- Have a history of frequent or intense sun exposure or sunburn
Preparing for your appointment
You're likely to start by seeing your family doctor or primary care doctor. However, in some cases when you call to set up an appointment, you may be referred to a specialist in skin diseases (dermatologist).
What to expect from your doctor
Your doctor is likely to ask you a number of questions, such as:
- When did you first notice the spots on your skin?
- Did the spots appear gradually or quickly?
- Have you noticed any other changes in the appearance of your skin?
- Is the condition itchy, tender or otherwise bothersome?
- Have you experienced frequent or severe sunburns?
- How often are you exposed to sun or UV radiation?
- Do you regularly protect your skin from UV radiation?
- What kind of sun protection do you use?
Questions for your doctor
Questions you may want to ask your doctor include:
- What suspicious changes in my skin should I look for?
- If the spots are, in fact, age spots, what can I do to improve the appearance?
- What results can I expect?
Tests and diagnosis
Diagnosing age spots may include:
- Visual inspection. Your doctor can usually diagnose age spots by visually inspecting your skin.
- Skin biopsy. If there's any doubt, your doctor may do other tests, such as a skin biopsy. During a skin biopsy, your doctor takes a small sample of your skin (biopsy) for microscopic analysis. A skin biopsy is usually done in a doctor's office, using a local anesthetic.
Other conditions that can look similar to age spots and that your doctor may need to rule out include the following:
- Moles. Although they often appear as small, dark brown spots, moles (nevi) vary in color and size. They can be raised or flat and can develop almost anywhere on your body.
- Seborrheic keratoses. These tan, brown or black growths have a wart-like or waxy, pasted-on appearance and range in size from very small to more than 1 inch (2.5 centimeters) across.
- Lentigo maligna. A type of skin cancer known as lentigo maligna melanoma can develop in areas of long-term sun exposure. Lentigo maligna starts as tan, brown or black lesions that slowly darken and enlarge. They tend to have an irregular border and uneven coloring, and they may be slightly raised.
Treatments and drugs
If you're unhappy with the appearance of age spots, treatments are available to lighten or remove them. Since the pigment is located at the base of the epidermis — the topmost layer of skin — any treatments meant to lighten the age spots must penetrate this layer of skin.
Age spot treatments include:
- Medications. Prescription bleaching creams (hydroquinone) used alone or with retinoids (tretinoin) and a mild steroid may gradually fade the spots over several months. Sun protection with a broad-spectrum sunscreen with a sun protection factor (SPF) of 30 is strongly advised if you use medication treatments. The treatments may result in temporary itching, redness, burning or dryness.
- Laser therapy. Laser therapy destroys melanin-producing cells (melanocytes) without damaging the skin's surface. Treatments with a laser typically require several sessions. After treatment, age spots fade gradually over several weeks or months. Laser therapy has few side effects, but it may result in slight discoloration of the skin.
- Freezing (cryotherapy). This procedure involves applying liquid nitrogen or another freezing agent to the age spots to destroy the extra pigment. As the area heals, the skin appears lighter. Freezing is typically used on a single age spot or a small grouping of age spots. The treatment may temporarily irritate the skin and poses a slight risk of permanent scarring or discoloration.
- Dermabrasion. This procedure consists of sanding down (planing) the surface layer of your skin with a rapidly rotating brush. This procedure removes the skin surface, and a new layer of skin grows in its place. Temporary redness and scab formation can result from this treatment.
- Chemical peel. A chemical peel involves applying an acid, which burns the outer layer of your skin, to the age spots. As your skin peels, new skin forms to take its place. Several treatments may be necessary before you notice any results. Sun protection is strongly advised following this treatment. Temporary irritation is likely, and there's a slight risk of discoloration.
Because age spot treatments are considered cosmetic, your insurance may not pay for them. And because the procedures can have side effects, discuss your options carefully with your dermatologist. Also, make sure your dermatologist is specially trained and experienced in the technique you're considering.
Lifestyle and home remedies
Many fade creams and lotions for lightening age spots are available in department stores, in drugstores and on the Internet. These may improve the appearance of age spots, depending on how dark the spots are and how often you apply the cream. Regular use over several weeks or months may be necessary to produce noticeable results.
If you opt for an over-the-counter (nonprescription) fade cream, choose one that contains hydroquinone, deoxyarbutin, glycolic acid or kojic acid. Note that some products, especially those that contain hydroquinone, may cause skin irritation.
To help avoid age spots, follow these tips for limiting your sun exposure:
- Avoid the sun between 10 a.m. and 4 p.m. Because the sun's rays are most intense during this time, try to schedule outdoor activities for other times of the day.
- Use sunscreen. Fifteen to 30 minutes before going outdoors, apply a broad-spectrum sunscreen that provides protection from both UVA and UVB light. Broad-spectrum sunscreens contain one or more of the following ingredients: avobenzone, cinoxate, ecamsule, menthyl anthranilate, octyl methoxycinnamate, octyl salicylate, oxybenzone, sulisobenzone, titanium dioxide or zinc oxide. Use a sunscreen with a sun-protection factor (SPF) of at least 15. Apply sunscreen generously, and reapply every two hours — or more often if you're swimming or perspiring.
- Cover up. For protection from the sun, wear a broad-brimmed hat, which provides more protection than does a baseball cap or golf visor, and tightly woven clothing that covers your arms and legs. You might also consider wearing clothing designed to provide sun protection. An ultraviolet protection factor (UPF) of 40 to 50 provides the best protection. UV-blocking clothes can lose their protective feature if they are stretched, become wet or are washed repeatedly.
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