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Tests and diagnosis

By Mayo Clinic staff

To evaluate whether you have an allergy, your doctor may:

  • Ask detailed questions about signs and symptoms
  • Perform a physical exam
  • Have you keep a detailed diary of symptoms and possible triggers

If you have a food allergy, your doctor may:

  • Ask you to keep a detailed diary of the foods you eat
  • Have you eliminate a food from your diet (elimination diet) — and then have you eat the food in question again to see if it causes a reaction

Your doctor may also recommend one or both of the following tests:

  • Skin test. In this test, your skin is pricked and exposed to small amounts of the proteins found in your potential allergen. If you're allergic, you'll likely develop a raised bump (hive) at the test location on your skin. Allergy specialists usually are best equipped to perform and interpret allergy skin tests.
  • Blood test. A blood test that's sometimes called the radioallergosorbent test (RAST) can measure your immune system's response to a specific allergen by measuring the amount of allergy-causing antibodies in your bloodstream, known as immunoglobulin E (IgE) antibodies. A blood sample is sent to a medical laboratory, where it can be tested for evidence of sensitivity to possible allergens.

If your doctor suspects your problems are caused by something other than an allergy, you may need other tests to identify — or rule out — other medical problems.

References
  1. Allergy overview. Asthma and Allergy Foundation of America. http://aafa.org/display.cfm?id=9. Accessed Oct. 25, 2012.
  2. Allergies. American Academy of Allergy, Asthma and Immunology. http://www.aaaai.org/conditions-and-treatments/allergies.aspx. Accessed Oct. 25, 2012.
  3. Allergic reactions: Tips to remember. American Academy of Allergy, Asthma and Immunology. http://www.aaaai.org/conditions-and-treatments/library/at-a-glance/allergic-reactions.aspx. Accessed Oct. 1, 2012.
  4. Pichler WJ. Drug allergy: Classification and clinical features. www.uptodate.com/index. Accessed Oct. 26, 2012.
  5. Bope ET, et al. Conn's Current Therapy. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4377-0986-5..C2009-0-38984-9--TOP&isbn=978-1-4377-0986-5&about=true&uniqId=236797353-5. Accessed Oct. 25, 2012.
  6. Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Oct. 25, 2012.
  7. Anaphylaxis: Tips to remember. American Academy of Allergy, Asthma and Immunology. http://www.aaaai.org/conditions-and-treatments/library/allergy-library/anaphylaxis.aspx. Accessed Oct. 25, 2012.
  8. Frequently asked questions. American College of Allergy, Asthma & Immunology. http://www.acaai.org/patients/faq/Pages/default.aspx . Accessed Oct. 25, 2012.
  9. Kim H, et al. Anaphylaxis. Allergy, Asthma and Clinical Immunology. 2011;7(suppl):S6.
  10. Kliegman RM, et al. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/208746819-6/0/1608/0.html. Accessed Oct. 26, 2012.
  11. Food allergies. Asthma and Allergy Foundation of America. http://www.aafa.org/display.cfm?id=9&sub=20&cont=286. Accessed Oct. 26, 2012.
  12. Is rinsing your sinuses safe? U.S. Food and Drug Administration. http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm316375.htm. Accessed Oct. 26, 2012.
  13. Indoor air quality and allergies. Asthma and Allergy Foundation of America. http://www.aafa.org/print.cfm?id=9&sub=18&cont=233. Accessed Oct. 26, 2012.
  14. Allergy. Natural Medicine Comprehensive Database. http://www.naturaldatabase.com. Accessed Oct. 26, 2012.
DS01118 Jan. 29, 2013

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