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Prevention

By Mayo Clinic staff

Alzheimer's Caregiving

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Right now, there's no proven way to prevent Alzheimer's disease. Research into prevention strategies is ongoing. The strongest evidence so far suggests that you may be able to lower your risk of Alzheimer's disease by reducing your risk of heart disease. Many of the same factors that increase your risk of heart disease can also increase your risk of Alzheimer's disease and vascular dementia. Important factors that may be involved include high blood pressure, high blood cholesterol, excess weight and diabetes.

New programs targeted to people at high risk of dementia are being developed. These multicomponent programs encourage physical activity, cognitive stimulation, social engagement and a healthy diet. They also teach memory compensation strategies that help optimize daily function even if brain changes progress. Keeping active — physically, mentally and socially — may make your life more enjoyable and may also help reduce the risk of Alzheimer's disease.

References
  1. Thies W, et al. 2012 Alzheimer's disease facts and figures. Alzheimer's & Dementia. 2012; 8:131.
  2. Halter JB, et al. Hazzard's Geriatric Medicine and Gerontology. 6th ed. New York, N.Y.: The McGraw-Hill Companies; 2009. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=540.. Accessed Nov. 18, 2012.
  3. Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4.. Accessed Nov. 18, 2012.
  4. Basics of Alzheimer's disease. Alzheimer's Association. http://www.alz.org/national/documents/brochure_basicsofalz_low.pdf. Accessed Dec. 19, 2012.
  5. Alzheimer's disease fact sheet. National Institute on Aging. http://www.nia.nih.gov/NR/rdonlyres/7DCA00DB-1362-4755-9E87-96DF669EAE20/13991/ADFactSheetFINAL2510.pdf. Accessed Nov. 18, 2012.
  6. Alzheimer's disease information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/alzheimersdisease/alzheimersdisease.htm. Accessed Dec. 13, 2012.
  7. Desai AK. Revitalizing the aging brain. Medical Clinics of North America. 2011;95:463.
  8. Caring for a person with Alzheimer's disease. National Institute on Aging. http://www.nia.nih.gov/alzheimers/publication/caring-person-alzheimers-disease/understanding-ad. Accessed Dec. 19, 2012.
  9. Essentials of a diagnostic workup. Alzheimer's Association. http://www.alz.org/professionals_and_researchers_14902.asp. Accessed Dec. 19, 2012.
  10. Nowrangi MA. Epidemiology, assessment and treatment of dementia. Psychiatric Clinics of North America. 2011;34:275.
  11. Alternative treatments. Alzheimer's Association. http://www.alz.org/alzheimers_disease_alternative_treatments.asp. Accessed Dec. 19, 2012.
  12. Preventing Alzheimer's disease and cognitive decline. National Institutes of Health State-of-the-Science Conference Statement. http://consensus.nih.gov/2010/alzstatement.htm. Accessed Dec. 19, 2012.
  13. Farina N, et al. Vitamin E for Alzheimer's dementia and mild cognitive impairment. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD002854.pub3/abstract. Accessed Dec. 10, 2012.
  14. Natural medicines in the clinical management of Alzheimer's disease. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Dec. 10, 2012.
DS00161 Jan. 19, 2013

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