Ambien: Is dependence a concern?

I've struggled with insomnia for years. Three months ago, my doctor prescribed Ambien, and it's worked great for me. But my doctor doesn't want to renew my prescription because she's afraid I might become dependent on it. Is that likely?

- No name / No state given

Mayo Clinic general health specialist Kenneth Berge, M.D., and colleagues answer select questions from readers.

Answer

Physiological dependence on zolpidem (Ambien) isn't thought to occur among otherwise healthy adults. In fact, Ambien misuse is almost exclusively limited to people who have a history of addiction. Although the Food and Drug Administration has only approved regular-release Ambien for short-term use, no time limits are associated with a newer controlled-release formulation of Ambien. Some studies suggest that Ambien is effective over the long term without adverse effects, and some doctors prescribe Ambien indefinitely, as long as careful follow-up is possible. If you have a history of addiction, however, long-term Ambien use might not be right for you.