Anaphylaxis

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Risk factors

By Mayo Clinic staff

There aren't many known risk factors for anaphylaxis, but some things that may increase your risk include:

  • A personal history of anaphylaxis. If you've experienced anaphylaxis once, your risk of having this serious reaction is increased. Future reactions may be more severe than the first reaction.
  • Allergies or asthma. People who have either condition are at increased risk of having anaphylaxis.
  • A family history. If you have family members who have experienced exercised-induced anaphylaxis, your risk of developing this type of anaphylaxis is higher than it is for someone without a family history.
References
  1. Austen KF. Allergies, anaphylaxis, and systemic mastocytosis. In: Fauci AS, et al. Harrison's Principles of Internal Medicine. 17th ed. New York, N.Y.: McGraw-Hill; 2008. http://www.accessmedicine.com/content.aspx?aID=2858746. Accessed June 2, 2010.
  2. Lieberman P, et al. The diagnosis and management of anaphylaxis: An updated practice parameter. Journal of Allergy and Clinical Immunology. 2005;115:S483.
  3. Tips to remember: Anaphylaxis. American Academy of Allergy, Asthma and Immunology. http://www.aaaai.org/patients/publicedmat/tips/whatisanaphylaxis.stm. Accessed June 4, 2010.
  4. Simons FE. Anaphylaxis. Journal of Allergy and Clinical Immunology. 2010;125:S161.
  5. Yamashita Y, et al. Cutting edge: Genetic variation influences Fc-epsilon RI-induced mast cell activation and allergic responses. The Journal of Immunology. 2007;179:740.
  6. Simons FE. Anaphylaxis: Evidence-based long-term risk reduction in the community. Immunology and Allergy Clinics of North America. 2007;27:231.
DS00009 Sept. 3, 2010

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