High blood pressure (hypertension)

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continued:

Angiotensin II receptor blockers

Uses for angiotensin II receptor blockers

Doctors prescribe these drugs to prevent, treat or improve symptoms in a variety of conditions, such as:

  • High blood pressure
  • Heart failure
  • Kidney failure in diabetes
  • Chronic kidney diseases
  • Hardening and thickening of the skin (scleroderma)

Side effects and cautions

Few people have side effects when taking angiotensin II receptor blockers, but possible side effects may include:

  • Headache
  • Dizziness
  • Lightheadedness
  • Nasal congestion
  • Back and leg pain
  • Diarrhea

Rare but more-serious side effects include:

  • Kidney failure
  • Liver failure
  • Allergic reaction
  • A drop in white blood cells
  • Localized swelling of tissues (angioedema)

Because angiotensin II receptor blockers can cause birth defects, don't take them if you are pregnant or plan to become pregnant.

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References
  1. Flynn JT. Treatment of high blood pressure: Drug therapy. In: Kaplan NM, et al. Kaplan's Clinical Hypertension. 10th ed. Philadelphia, Pa.: Wolters Kluwer Health Lippincott Williams & Wilkins; 2010:192.
  2. Types of blood pressure medications. American Heart Association. http://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Types-of-Blood-Pressure-Medications_UCM_303247_Article.jsp. Accessed Sept. 30, 2010.
  3. High blood pressure: Medicines to help you. U.S. Food and Drug Administration. http://www.fda.gov/forconsumers/byaudience/forwomen/ucm118594.htm. Accessed Sept. 30, 2010.
  4. Kaplan NM, et al. Indications and contraindications to the use of specific antihypertensive drugs. http://www.uptodate.com/home/index.html. Accessed Sept. 30, 2010.
  5. Chobanian AV, et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. New England Journal of Medicine. 2003;289:2560.
HI00054 June 7, 2011

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