High blood pressure (hypertension)

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Angiotensin II receptor blockers

Uses for angiotensin II receptor blockers

Doctors prescribe these drugs to prevent, treat or improve symptoms in a variety of conditions, such as:

  • High blood pressure
  • Heart failure
  • Kidney failure in diabetes
  • Chronic kidney diseases
  • Hardening and thickening of the skin (scleroderma)

Side effects and cautions

Few people have side effects when taking angiotensin II receptor blockers, but possible side effects may include:

  • Headache
  • Dizziness
  • Lightheadedness
  • Nasal congestion
  • Back and leg pain
  • Diarrhea

Rare but more serious side effects include:

  • Kidney failure
  • Liver failure
  • Allergic reaction
  • A drop in white blood cells
  • Localized swelling of tissues (angioedema)

Because angiotensin II receptor blockers can cause birth defects, don't take them if you're pregnant or plan to become pregnant.

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References
  1. Reeder GS. Angiotensin converting enzyme inhibitors and receptor blockers in acute myocardial infarction: Recommendations for use. http://www.uptodate.com/index. Accessed Nov. 13, 2008.
  2. Colucci WS. Angiotensin converting enzyme inhibitors and receptor blockers in heart failure: Mechanisms of action. http://www.uptodate.com/index. Accessed Nov. 13, 2008.
  3. Initial antihypertensive therapy: Drugdex Consults. Micromedex Healthcare Series. http://www.micromedex.com/. Accessed Nov. 12, 2008.
  4. Blood pressure-lowering drugs. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=159. Accessed Nov. 12, 2008.
  5. Sheps SG, ed. Mayo Clinic 5 Steps to Controlling High Blood Pressure. Rochester, Minn.: Mayo Foundation for Medical Education and Research;2008:190.

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Dec. 18, 2008

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