Risk factors
By Mayo Clinic staff- Your sex. Men are more likely to develop ankylosing spondylitis than are women.
- Your age. Onset generally occurs in late adolescence or early adulthood.
- Your heredity. Most people who have ankylosing spondylitis have the HLA-B27 gene. But many people who have this gene never develop ankylosing spondylitis.
References
- Braveman SE. Ankylosing spondylitis. In: Frontera WR, et al. Essentials of Physical Medicine and Rehabilitation: Musculoskeletal Disorders, Pain, and Rehabilitation. 2nd ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4160-4007-1..50112-7&isbn=978-1-4160-4007-1&type=bookPage§ionEid=4-u1.0-B978-1-4160-4007-1..50112-7--cesec5&uniqId=228570791-3. Accessed Nov. 30, 2010.
- Yu DT. Clinical manifestations of ankylosing spondylitis in adults. http://www.uptodate.com/home/index.html. Accessed Nov. 30, 2010.
- Mercier LT. Ankylosing spondylitis. In: Ferri FF. Ferri's Clinical Advisor 2011: Instant Diagnosis and Treatment. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-0-323-05610-6..00010-X--sc0225&isbn=978-0-323-05610-6&sid=1090462943&type=bookPage§ionEid=4-u1.0-B978-0-323-05610-6..00010-X--sc0225&uniqId=228720493-4#4-u1.0-B978-0-323-05610-6..00010-X--sc0225. Accessed Nov. 30, 2010.
- Yu DT. Treatment and prognosis of ankylosing spondylitis in adults. http://www.uptodate.com/home/index.html. Accessed Nov. 30, 2010.
- Inman RD. Clinical subsets of the spondyloarthropathies: Ankylosing spondylitis. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4160-2805-5..50291-3--cesec29&isbn=978-1-4160-2805-5&sid=1090462943&type=bookPage§ionEid=4-u1.0-B978-1-4160-2805-5..50291-3--cesec33&uniqId=228720493-4#4-u1.0-B978-1-4160-2805-5..50291-3--cesec33. Accessed Nov. 30, 2010.
- Van der Linden SM, et al. Ankylosing spondylitis. In: Firestein GS, et al. Kelley's Textbook of Rheumatology. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2009. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4160-3285-4..10070-1&isbn=978-1-4160-3285-4&sid=1090462943&type=bookPage§ionEid=4-u1.0-B978-1-4160-3285-4..10070-1&uniqId=228720493-4#4-u1.0-B978-1-4160-3285-4..10070-1. Accessed Nov. 30, 2010.


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