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Tests and diagnosis

By Mayo Clinic staff

Your doctor will first want to rule out other, more common conditions that may be causing your signs and symptoms, such as flu (influenza) or pneumonia. You may have a rapid flu test to quickly diagnose a case of influenza. If other tests are negative, you may have further tests to look specifically for anthrax, such as:

  • Skin testing. A sample of fluid from a suspicious lesion on your skin or a small tissue sample (biopsy) may be tested in a lab for signs of cutaneous anthrax.
  • Blood tests. You may have a small amount of blood drawn that's checked in a lab for anthrax bacteria.
  • Chest X-ray or computerized tomography (CT) scan. Your doctor may request a chest X-ray or CT scan to help diagnose inhalation anthrax.
  • Endoscopy and stool samples. To diagnose intestinal anthrax, your doctor may examine your throat or intestine with an endoscope — a thin, flexible tube with a tiny camera at its tip. In some cases, a sample of your stool may be checked for anthrax bacteria.
  • Spinal tap (lumbar puncture). In this test, your doctor inserts a needle into your spinal canal and withdraws a small amount of fluid. A spinal tap is usually done only to confirm a diagnosis of anthrax meningitis.
References
  1. Anthrax. Centers for Disease Control and Prevention. http://www.cdc.gov/nczved/divisions/dfbmd/diseases/anthrax/. Accessed April 30, 2011.
  2. Anthrax. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/sec14/ch172/ch172b.html. Accessed April 30, 2011.
  3. Wilson K. Clinical manifestations and diagnosis of anthrax. http://www.uptodate.com/home/index.html. Accessed April 30, 2011.
  4. Wilson K. Microbiology, pathogenesis, and epidemiology of anthrax. http://www.uptodate.com/home/index.html. Accessed April 30, 2011.
  5. Anthrax vaccine: What you need to know. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/pubs/vis/downloads/vis-anthrax.pdf. Accessed April 30, 2011.
  6. Wilson K. Treatment of anthrax. http://www.uptodate.com/home/index.html. Accessed April 30, 2011.
  7. Ferri FF. Anthrax. In: Ferri's Clinical Advisor 2011: Instant Diagnosis and Treatment. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-05610-6..C2009-0-38600-6--TOP&isbn=978-0-323-05610-6&about=true&uniqId=230100505-53. Accessed April 30, 2011.
  8. Wilson K. Prevention of anthrax. http://www.uptodate.com/home/index.html. Accessed April 30, 2011.
DS00422 June 9, 2011

© 1998-2013 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

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