Antibiotic-associated diarrhea

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Risk factors

By Mayo Clinic staff

Antibiotic-associated diarrhea can occur in anyone who undergoes antibiotic therapy. But you're more likely to develop antibiotic-associated diarrhea if you:

  • Previously experienced antibiotic-associated diarrhea while taking an antibiotic medication
  • Are age 65 or older
  • Have had surgery on your intestinal tract
  • Have recently stayed in a hospital or nursing home
  • Have a serious underlying illness affecting your intestines, such as colon cancer or inflammatory bowel disease
Complications Causes

  • See Also

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  • Diarrhea
References
  1. Kelly CP, et al. Antibiotic-associated diarrhea, pseudomembranous enterocolitis and Clostridium difficile-associated diarrhea and colitis. In: Feldman M, et al. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2006. http://www.mdconsult.com/das/book/body/189880460-5/0/1389/0.html. Accessed March 19, 2010.
  2. Ferri FF. Pseudomembranous colitis. In: Ferri FF. Ferri's Clinical Advisor 2010. Philadelphia, Pa.: Mosby; 2010. http://www.mdconsult.com/das/book/body/189880460-5/0/2088/0.html. Accessed March 19, 2010.
  3. Thielman NM, et al. Antibiotic-associated colitis. In: Mandell GL, et al. Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa.: Churchill Livingstone; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-443-06839-3..X0001-X--TOP&isbn=978-0-443-06839-3&uniq=190074036#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-0-443-06839-3..X0001-X--TOP%3Bfrom%3Dcontent%3Bisbn%3D978-0-443-06839-3%3Btype%3DbookHome. Accessed March 19, 2010.
  4. O'Mahony S, et al. Enteric bacterial flora and bacterial overgrowth. In: Feldman M, et al. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2006. http://www.mdconsult.com/das/book/body/189880460-5/0/1389/0.html. Accessed March 26, 2010.
  5. Diarrhea. National Institute for Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/diarrhea/index.htm. Accessed March 25, 2010.
  6. Peterson MA. Disorders of the large intestine. In: Marx JA, et al. Rosen's Emergency Medicine: Concepts and Clinical Practice. 7th ed. Philadelphia, Pa.: Mosby; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-323-05472-0..X0001-1--TOP&isbn=978-0-323-05472-0&uniq=191219029#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-0-323-05472-0..X0001-1--TOP%3Bfrom%3Dcontent%3Bisbn%3D978-0-323-05472-0%3Btype%3DbookHome. Accessed March 25, 2010.
  7. Diarrhea. ADA Nutrition Care Manual. http://nutritioncaremanual.org/topic.cfm?ncm_heading=Nutrition%20Care&ncm_toc_id=19099. Accessed March 26, 2010.
  8. Parkes GC, et al. The mechanisms and efficacy of probiotics in the prevention of Clostridium difficile-associated diarrhoea. Lancet Infectious Diseases. 2009;9:237.
DS00454 May 8, 2010

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