• image.alt
  • With Mayo Clinic internist

    James M. Steckelberg, M.D.

    read biography
The Mayo Clinic Diet Book, learn more

Free

E-newsletter

Subscribe to Housecall

Our weekly general interest
e-newsletter keeps you up to date on a wide variety of health topics.

Sign up now

Question

Antibiotics and alcohol: Should I avoid mixing them?

What are the effects of drinking alcohol while taking antibiotics?

Answer

from James M. Steckelberg, M.D.

Antibiotics and alcohol can cause similar side effects, such as stomach upset, dizziness and drowsiness. Combining antibiotics and alcohol can increase these side effects.

A few antibiotics — such as metronidazole (Flagyl), tinidazole (Tindamax) and trimethoprim-sulfamethoxazole (Bactrim) — should not be mixed with alcohol because this may result in a more severe reaction. Drinking any amount of alcohol with these medications can result in side effects such as flushing, headache, nausea and vomiting, and rapid heart rate.

Keep in mind that some cold medicines and mouthwashes also contain alcohol. So check the label and avoid such products while taking these antibiotics.

Although alcohol doesn't reduce the effectiveness of most antibiotics, it can reduce your energy and delay how quickly you recover from illness. So, it's a good idea to avoid alcohol until you finish your antibiotics and are feeling better.

Next question
Grapefruit juice: Beware of dangerous medication interactions
References
  1. Masters SB. Basic pharmacology of ethanol. In: Katzung BG, et al. Basic and clinical pharmacology. 11th ed. New York, N.Y.: The McGraw-Hill Companies; 2009
  2. Steckelberg JM (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 3, 2012.
  3. Flagyl (prescribing information). New York, N.Y.: Pfizer Inc.; 2010. http://www.pfizer.com/products/rx/rx_product_flagyl.jsp. Accessed Dec. 23, 2011.
  4. Tindamaz (prescribing information). San Antonio, Texas: Mission Pharmacal Co.; 2007. http://www.tindamax.com/For_Health_Professionals/Index.aspx. Accessed Dec. 23, 2011.
  5. Bactrim and alcohol. Thomson Micromedex. http://www.thomsonhc.com/micromedex2/librarian/PFDefaultActionId/evidencexpert.ShowDrugInteractionsResults#. Accessed Dec. 23, 2011.
AN01802 March 3, 2012

© 1998-2013 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

  • Reprints
  • Print
  • Share on:

  • Email

Advertisement


Text Size: smaller largerlarger