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continued:

Antidepressants: Are they safe during pregnancy?

Are there any other risks for the baby?

If you take antidepressants throughout pregnancy or during the last trimester, your baby may experience temporary withdrawal symptoms — such as jitters or irritability — at birth.

A preliminary 2007 study associated the use of antidepressants during pregnancy with preterm birth. However, the evidence wasn't strong enough to consider antidepressants a consistent risk for preterm birth. Generally, antidepressants aren't considered a risk factor for preterm birth.

What happens if I stop taking antidepressants during pregnancy?

If you stop taking antidepressants during pregnancy, you risk a depression relapse. In fact, in a 2006 study, pregnant women who stopped taking antidepressants were five times more likely to experience a depression relapse than were pregnant women who continued taking the drugs.

In addition, stopping an SSRI abruptly may cause various signs and symptoms, including:

  • Headache
  • Nausea and vomiting
  • Chills
  • Dizziness
  • Fatigue
  • Insomnia
  • Irritability
  • Vivid dreams

What's the bottom line?

If you have depression and are pregnant or thinking about getting pregnant, consult your doctor. Sometimes mild depression can be managed with support groups, counseling or other therapies. If your depression is severe or you have a recent history of depression, the risk of relapse may be greater than the risks associated with antidepressants.

It's not an easy decision. As researchers continue to learn more about antidepressants, the risks and benefits of taking the drugs during pregnancy must be weighed carefully on a case-by-case basis. Work with your doctor to make an informed choice that gives you — and your baby — the best chance for long-term health.

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Dec. 18, 2007

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