Risk factorsBy Mayo Clinic staff
Risk factors for antiphospholipid syndrome include:
- Having an autoimmune condition, such as lupus or Sjogren's syndrome. This increases your risk of developing antiphospholipid antibodies.
- Having certain infections, such as syphilis or hepatitis C.
- Taking certain medications, such as hydralazine for high blood pressure.
- Having a family member with antiphospholipid syndrome.
Antiphospholipid syndrome occurs most frequently in young to middle-aged women, although it can occur at any age and also affects men.
Risk factors for developing symptoms
It's possible to have the antibodies associated with antiphospholipid syndrome without ever developing signs or symptoms. However, if you have these antibodies, your risk of developing blood clots increases particularly if you:
- Become pregnant
- Remain immobile for a period of time (such as sitting during a long airline flight)
- Undergo surgery
- Smoke cigarettes
- Have high blood pressure or high cholesterol
- Take oral contraceptives
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