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Treatments and drugs

By Mayo Clinic staff

The two main treatments for anxiety disorders are medications and psychological counseling (psychotherapy). You may benefit most from a combination of the two. It may take some trial and error to discover exactly what treatments work best for you.

Medications
Several different types of medications are used to treat anxiety disorders. These include:

  • Antidepressants. These medications influence the activity of brain chemicals (neurotransmitters) thought to play a role in anxiety disorders. Examples of antidepressants used to treat anxiety disorders include fluoxetine (Prozac), paroxetine (Paxil), escitalopram (Lexapro), sertraline (Zoloft), venlafaxine (Effexor) and imipramine (Tofranil).
  • Buspirone. This anti-anxiety medication may be used on an ongoing basis. As with most antidepressants, it typically takes up to several weeks to become fully effective. A common side effect of buspirone is a feeling of lightheadedness shortly after taking it. Less common side effects include headaches, nausea, nervousness and insomnia.
  • Benzodiazepines. In limited circumstances your doctor may prescribe one of these sedatives for relief of anxiety symptoms. Examples include clonazepam (Klonopin), lorazepam (Ativan), diazepam (Valium), chlordiazepoxide (Librium) and alprazolam (Xanax). Benzodiazepines are generally used only for relieving acute anxiety on a short-term basis. Because they can be habit-forming, these medications aren't a good choice if you've had problems with alcohol or drug abuse (making you more prone to addiction). They can cause side effects that include drowsiness, reduced coordination, and problems with balance and memory.

Psychotherapy
Also known as talk therapy and psychological counseling, psychotherapy involves working out underlying life stresses and concerns and making behavior changes. It can be an effective treatment for anxiety.

Cognitive behavioral therapy is one of the most common types of psychotherapy for anxiety disorders. Generally a short-term treatment, cognitive behavioral therapy focuses on teaching you specific skills to identify negative thoughts and behaviors and replace them with positive ones. Even if an undesirable situation doesn't change, you can reduce stress and gain more control over your life by changing the way you respond.

References
  1. Anxiety disorders. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Arlington, Va.: American Psychiatric Association; 2000. http://www.psychiatryonline.com. Accessed May 18, 2010.
  2. Hollander E, et al. Anxiety disorders. In: Hales RE, et al. Textbook of Psychiatry. 5th ed. Arlington, Va.: American Psychiatric Publishing; 2008. http://www.psychiatryonline.com/content.aspx?aID=335698. Accessed May 18, 2010.
  3. Katon W, et al. Anxiety disorders. In: Rakel R. Textbook of Family Medicine. 7th ed. Philadelphia, Pa.: Saunders; 2007. http://www.mdconsult.com/das/book/body/202053603-6/0/1481/624.html?tocnode=53395. Accessed May 18, 2010.
  4. Kercher EE, et al. Anxiety disorders. In: Marx JM, et al. Rosen's Emergency Medicine. 7th ed. Philadelphia, Pa.: Mosby; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-0-323-05472-0..00110-9--s0025&uniq=202069582&isbn=978-0-323-05472-0. Accessed May 18, 2010.
  5. Hettema JM, et al. The structure of genetic and environmental risk factors for anxiety disorders in men and women. Archives of General Psychiatry. 2005;62:182.
  6. Hoffman EJ, et al. Anxiety disorders: A comprehensive review of pharmacotherapies. Mount Sinai Journal of Medicine. 2008;75:248.
  7. Roy-Byrne PP, et al. Anxiety disorders and comorbid medical illness. General Hospital Psychiatry. 2008;30:208.
  8. Lee RA. Anxiety disorders. In: Rakel D. Integrative Medicine. 2nd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/154207005-3/0/1494/57.html?tocnode=54111716&fromURL=57.html#4-u1.0-B978-1-4160-2954-0..50014-4_229. Accessed May 18, 2010.
  9. Saeed SA, et al. Herbal and dietary supplements for treatment of anxiety disorders. American Family Physician. 2007;76:549.
  10. Donker T, et al. Psychoeducation for depression, anxiety and psychological distress: A meta-analysis. BMC Medicine. 2009;7:79.
DS01187 June 29, 2010

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