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Risk factors

By Mayo Clinic staff

Aortic valve stenosis usually isn't preventable. Some people are born with an already narrowed aortic valve or develop aortic valve stenosis later in life because they were born with a bicuspid aortic valve — one with two flaps (leaflets) instead of three. A bicuspid aortic valve is a major risk factor for aortic valve stenosis.

Aortic valve stenosis also may be related to age and the buildup of calcium deposits on heart valves or a history of rheumatic fever.

References
  1. Aortic valve stenosis (AS) and aortic insufficiency (AI). American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=1659. Accessed July 6, 2009.
  2. Aortic stenosis. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec07/ch076/ch076c.html. Accessed July 6, 2009.
  3. Grimard BH, et al. Aortic stenosis: Diagnosis and treatment. American Family Physician. 2008;78:717.
  4. Otto CM, et al. Valvular heart disease. In: Libby P, et al., eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-1-4160-4106-1..50065-0&uniq=148441160&isbn=978-1-4160-4106-1&sid=860585891. Accessed July 6, 2009.
  5. Otto CM. Pathophysiology and clinical features of valvular aortic stenosis in adults. http://www.uptodate.com/home/index.html. Accessed July 6, 2009.
  6. Ardehali R, et al. Valvular heart disease. In: Nilsson KR, et al. The Osler Medical Handbook. Philadelphia, Pa.: Saunders Elsevier; 2006. http://www.mdconsult.com/das/book/body/148441160-4/860446560/1387/28.html#4-u1.0-B0-323-03748-8..50017-8_181. Accessed July 6, 2009.
  7. Carabello BA. Valvular heart disease. In: Goldman L, et al., eds. Goldman: Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/148441160-6/860446560/1492/318.html#4-u1.0-B978-1-4160-2805-5..50080-X_3105. Accessed July 6, 2009.
  8. Otto CM. Medical therapy in asymptomatic aortic stenosis in adults. http://www.uptodate.com/home/index.html. Accessed July 6, 2009.
  9. Grogan M (expert opinion). Mayo Clinic, Rochester, Minn. July 19, 2009.

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Sept. 24, 2009

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