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Tests and diagnosis

By Mayo Clinic staff

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Illustration showing a needle suctioning out liquid bone marrow from the hipbone 
Bone marrow biopsy

To diagnose aplastic anemia, your doctor may recommend:

  • Blood tests. Normally, red blood cell, white blood cell and platelet levels stay within a certain range. Your doctor may suspect aplastic anemia when all three of these blood cell levels are very low.
  • Bone marrow biopsy. To confirm a diagnosis, you'll need to undergo a bone marrow biopsy. In this procedure, a doctor uses a needle to remove a small sample of bone marrow from a large bone in your body, such as your hipbone. The bone marrow sample is examined under a microscope to rule out other blood-related diseases. In aplastic anemia, bone marrow contains fewer blood cells than normal.

Once you've received a diagnosis of aplastic anemia, you may need additional tests to determine an underlying cause.

References
  1. Young NS, et al. Aplastic anemia. In: Hoffman R, et al. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2009. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-443-06715-0..X5001-8--TOP&isbn=978-0-443-06715-0&uniqId=230100505-56. Accessed Jan. 24, 2011.
  2. Aplastic anemia. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/aplastic/aplastic_all.html. Accessed Jan. 24, 2011.
DS00322 March 5, 2011

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