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    Thomas Behrenbeck, M.D.

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Question

Arcus senilis: A sign of high cholesterol?

What's the relationship between arcus senilis and high cholesterol?

Answer

from Thomas Behrenbeck, M.D.

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Photo of arcus senilis 
Arcus senilis

Arcus senilis and the eye findings associated with high cholesterol are distinctly different.

Arcus senilis, also known as arcus cornealis, is a gray or white arc visible above and below the outer part of the cornea — the clear, dome-like covering over the front of the eye. Eventually, the arc may evolve into a complete ring around the cornea. Arcus senilis is common in older adults. It's caused by fat (lipid) deposits deep in the edge of the cornea. It isn't necessarily related to high cholesterol, however. Arcus senilis doesn't affect vision, nor does it require treatment.

High cholesterol is more likely associated with a similar gray or white arc visible around the entire cornea (circumferential arcus) in younger adults. Even then, however, eye findings associated with high cholesterol are uncommon — typically affecting only people who have severe cases of high cholesterol and high triglycerides passed down through families (familial hyperlipidemia). Treatment is generally aimed at controlling cholesterol and triglyceride levels.

The average person who has high cholesterol doesn't develop an arc of any type. If you're concerned about eye health and high cholesterol, consult your doctor for an evaluation.

Next question
Cholesterol level: Can it be too low?
References
  1. Zech LA, et al. Correlating corneal arcus with atherosclerosis in familial hypercholesterolemia. Lipids in Health and Disease. 2008;7:7.
  2. Rumelt S, et al. Double arcus cornealis. Eye. 2004;18:1020.
  3. Fernandez A, et al. Corneal arcus as coronary artery disease risk factor. Atherosclerosis. 2007;193:235.
  4. Chua BE, et al. Corneal arcus and hyperlipidemia: Findings from an older population. American Journal of Ophthalmology. 2004;137:363.
  5. Gau GT (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 19, 2008.

AN01493

Dec. 17, 2008

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