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Risk factors

By Mayo Clinic staff

Risk factors for arthritis include:

  • Family history. Some types of arthritis run in families, so you may be more likely to develop arthritis if your parents or siblings have the disorder. Your genes can make you more susceptible to environmental factors that may trigger arthritis.
  • Age. The risk of many types of arthritis — including osteoarthritis, rheumatoid arthritis and gout — increases with age.
  • Sex. Women are more likely than are men to develop rheumatoid arthritis, while most of the people who have gout are men.
  • Previous joint injury. People who have injured a joint, perhaps while playing a sport, are more likely to eventually develop arthritis in that joint.
  • Obesity. Carrying excess pounds puts stress on joints, particularly your knees, hips and spine. Obese people have a higher risk of developing arthritis.
References
  1. Arthritis. National Institute of Arthritis and Musculoskeletal Diseases. http://www.niams.nih.gov/Health_Info/Arthritis/arthritis_rheumatic_aqa.asp. Accessed Nov. 18, 2010.
  2. Arthritis advice. National Institute on Aging. http://www.nia.gov/HealthInformation/Publications/arthritis.htm. Accessed Nov. 18, 2010.
  3. Arend WP, et al. Approach to the patient with rheumatic disease. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4160-2805-5..50282-2&isbn=978-1-4160-2805-5&type=bookPage&sectionEid=4-u1.0-B978-1-4160-2805-5..50282-2&uniqId=227265748-3. Accessed Nov. 18, 2010.
  4. Arthritis: Frequently asked questions - General public. Centers for Disease Control and Prevention. http://www.cdc.gov/arthritis/basics/faqs.htm. Accessed Nov. 18, 2010.
  5. Davis JM, et al. History and physical examination of the musculoskeletal system. In: Firestein GS, et al. Kelley's Textbook of Rheumatology. 8th ed. Philadelphia, Pa.: W.B. Saunders Co.; 2008. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4160-3285-4..10035-X&isbn=978-1-4160-3285-4&type=bookPage&sectionEid=4-u1.0-B978-1-4160-3285-4..10035-X&uniqId=227265748-3#4-u1.0-B978-1-4160-3285-4..10035-X. Accessed Nov. 18, 2010.
  6. Schur PH, et al. General principles of management of rheumatoid arthritis. http://uptodate.com/home/index.html. Accessed Nov. 18, 2010.
  7. Weissman BN, et al. Diagnostic imaging of joint pain. http://www.uptodate.com/home/index.html. Accessed Nov. 18, 2010.
  8. Chang-Miller A (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 27, 2010.
  9. Kalunian KC. Pharmacologic therapy of osteoarthritis. http://www.uptodate.com/home/index.html. Accessed Nov. 18, 2010.
  10. Kalunian KC. Nonpharmacologic therapy of osteoarthritis. http://www.uptodate.com/home/index.html. Accessed Nov. 18, 2010.
  11. Chronic pain and CAM: At a glance. National Center for Complementary and Alternative Medicine. http://nccam.nih.gov/health/pain/chronic.htm. Accessed Nov. 19, 2010.
  12. Sawitzke AD, et al. Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT. Annals of Rheumatic Diseases. 2010;69:1459.
DS01122 Jan. 22, 2011

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