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Tests and diagnosis

By Mayo Clinic staff

Depending on the type of arthritis suspected, your doctor may suggest some of the following tests.

Laboratory tests
The analysis of different types of body fluids can help pinpoint the type of arthritis you may have. Fluids commonly analyzed include:

  • Blood
  • Urine
  • Joint fluid

To obtain a sample of your joint fluid, your doctor will cleanse and numb the area before inserting a needle in your joint space to withdraw some fluid.

Imaging
These types of tests can detect problems within your joint that may be causing your symptoms. Examples include:

  • X-rays. Using low levels of radiation to visualize bone, X-rays can show cartilage loss, bone damage and bone spurs. X-rays may not reveal early arthritic damage, but they are often used to track progression of the disease.
  • Computerized tomography (CT). CT scanners take X-rays from many different angles and combine the information to create cross-sectional views of internal structures. CTs can visualize both bone and the surrounding soft tissues.
  • Magnetic resonance imaging (MRI). Combining radio waves with a strong magnetic field, MRI can produce more-detailed cross-sectional images of soft tissues such as cartilage, tendons and ligaments.
  • Ultrasound. Using sound waves to create images of both hard and soft tissues within the body, ultrasound can help determine needle placement if your doctor wants to withdraw fluid from your joint or inject medicine.

Arthroscopy
In some cases, your doctor may look for damage in your joint by inserting a small, flexible tube — called an arthroscope — through an incision near your joint. The arthroscope transmits images from inside the joint to a video screen.

References
  1. Arthritis. National Institute of Arthritis and Musculoskeletal Diseases. http://www.niams.nih.gov/Health_Info/Arthritis/arthritis_rheumatic_aqa.asp. Accessed Nov. 18, 2010.
  2. Arthritis advice. National Institute on Aging. http://www.nia.gov/HealthInformation/Publications/arthritis.htm. Accessed Nov. 18, 2010.
  3. Arend WP, et al. Approach to the patient with rheumatic disease. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4160-2805-5..50282-2&isbn=978-1-4160-2805-5&type=bookPage&sectionEid=4-u1.0-B978-1-4160-2805-5..50282-2&uniqId=227265748-3. Accessed Nov. 18, 2010.
  4. Arthritis: Frequently asked questions - General public. Centers for Disease Control and Prevention. http://www.cdc.gov/arthritis/basics/faqs.htm. Accessed Nov. 18, 2010.
  5. Davis JM, et al. History and physical examination of the musculoskeletal system. In: Firestein GS, et al. Kelley's Textbook of Rheumatology. 8th ed. Philadelphia, Pa.: W.B. Saunders Co.; 2008. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4160-3285-4..10035-X&isbn=978-1-4160-3285-4&type=bookPage&sectionEid=4-u1.0-B978-1-4160-3285-4..10035-X&uniqId=227265748-3#4-u1.0-B978-1-4160-3285-4..10035-X. Accessed Nov. 18, 2010.
  6. Schur PH, et al. General principles of management of rheumatoid arthritis. http://uptodate.com/home/index.html. Accessed Nov. 18, 2010.
  7. Weissman BN, et al. Diagnostic imaging of joint pain. http://www.uptodate.com/home/index.html. Accessed Nov. 18, 2010.
  8. Chang-Miller A (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 27, 2010.
  9. Kalunian KC. Pharmacologic therapy of osteoarthritis. http://www.uptodate.com/home/index.html. Accessed Nov. 18, 2010.
  10. Kalunian KC. Nonpharmacologic therapy of osteoarthritis. http://www.uptodate.com/home/index.html. Accessed Nov. 18, 2010.
  11. Chronic pain and CAM: At a glance. National Center for Complementary and Alternative Medicine. http://nccam.nih.gov/health/pain/chronic.htm. Accessed Nov. 19, 2010.
  12. Sawitzke AD, et al. Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT. Annals of Rheumatic Diseases. 2010;69:1459.
DS01122 Jan. 22, 2011

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