Definition
By Mayo Clinic staffAsperger's syndrome is a developmental disorder that affects a person's ability to socialize and communicate effectively with others. Children with Asperger's syndrome typically exhibit social awkwardness and an all-absorbing interest in specific topics.
Doctors group Asperger's syndrome with other conditions that are called autistic spectrum disorders or pervasive developmental disorders. These disorders all involve problems with social skills and communication. Asperger's syndrome is generally thought to be at the milder end of this spectrum.
While there's no cure for Asperger's syndrome, if your child has the condition treatment can help him or her learn how to interact more successfully in social situations.
- Asperger's disorder. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. Arlington, Va.: American Psychiatric Association; 2000. http://psychiatryonline.com/content.aspx?aID=7667&searchStr=asperger%27s+disorder. Accessed Sept. 10, 2010.
- Toth K, et al. Asperger's syndrome: Diagnosis and treatment. American Journal of Psychiatry. 2008;165:958.
- Autism spectrum disorders. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec19/ch299/ch299c.html#S19_CH299_T002. Accessed Sept. 11, 2010.
- Asperger syndrome fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/asperger/detail_asperger.htm?css=print. Accessed Sept 11, 2010.
- Notordaeme M, et al. Asperger's syndrome and high-functioning autism: Language, motor and cognitive profiles. European Child and Adolescent Psychiatry. 2010;19:475.
- Asperger syndrome. National Institute of Child Health and Human Development. http://www.nichd.nih.gov/health/topics/asperger_syndrome.cfm. Accessed Sept. 11, 2010.
- Weber K. Asperger's syndrome: From hiding to thriving. The Nurse Practitioner. 2008;19:14.
- Levy SE, et al. Complementary and alternative medicine treatments for children with autism spectrum disorders. Child and Adolescent Psychiatry Clinics of North America. 2008;17:803.
- Price CS, et al. Prenatal and infant exposure to thimerosal from vaccines and immunoglobulins and risk of autism. Pediatrics. 2010;126:656.
- Atkinson DL (expert opinion). Mayo Clinic, Rochester, Minn. Oct. 25, 2010.
- Stigler KA, et al. Aripiprazole in pervasive developmental disorder not otherwise specified and Asperger's disorder: A 14-week, perspective, open-label study. Journal of Child and Adolescent Psychopharmacology. 2009;19:265.
- Posey DJ, et al. Guanfacine treatment of hyperactivity and inattention in pervasive developmental disorders: A retrospective analysis of 80 cases. Journal of Child and Adolescent Psychopharmacology. 2004;14:233.
- Moreno C, et al. Metabolic effects of second-generation antipsychotics in bipolar youth: Comparison with other psychotic and nonpsychotic diagnoses. Bipolar Disorders. 2010;12:172.
- Malone RP, et al. Advances in drug treatments for children and adolescents with autism and other pervasive developmental disorders. CNS Drugs. 2005;19:923.
- Elchaar GM, et al. Efficacy and safety of naltrexone use in pediatric patients with autistic disorder. Annals of Pharmacotherapy. 2006;40:1086.
- Questions and answers on unapproved chelation products. Food and Drug Administration. http://www.fda.gov/Drugs/ResourcesForYou/Consumers/BuyingUsingMedicineSafely/MedicationHealthFraud/ucm229313.htm. Accessed Oct. 26, 2010.
- Guastella AJ, et al. Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders. Biological Psychiatry. 2010;67:692.
- Hollander E, et al. Oxytocin increases retention of social cognition in autism. Biological Psychiatry. 2007;61:498.


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