Aspergillosis

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Complications

By Mayo Clinic staff

Depending on the type of infection, aspergillosis can cause a variety of serious complications:

  • Bone destruction and spread of infection. An aspergillus infection in your sinuses can destroy facial bones. It can also spread beyond your sinuses, and may be life-threatening if you have a weakened immune system.
  • Bleeding. Both aspergillomas and invasive aspergillosis can cause massive, and sometimes fatal, bleeding in your lungs.
  • Systemic infection. The most serious complication of aspergillosis is the spread of the infection to other parts of your body, especially your brain, heart and kidneys. Invasive aspergillosis spreads rapidly and is often fatal in spite of early treatment.
References
  1. Stevens DA. Aspergillosis. In: Goldman L, et al., eds. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/126486890-3/0/1492/0.html. Accessed March 15, 2009.
  2. Aspergillosis. Centers for Disease Control and Prevention. http://www.cdc.gov/nczved/dfbmd/disease_listing/aspergillosis_gi.html. Accessed March 15, 2009.
  3. Davies SF, et al. Fungal infections. In: Mason RJ, et al. Murray & Nadel's Textbook of Respiratory Medicine. 4th ed. St. Louis, Mo.: W.B. Saunders; 2005. http://www.mdconsult.com/das/book/body/126486890-4/817667210/1288/304.html#4-u1.0-B0-7216-0327-0..50037-9--cesec55_2038. Accessed March 15, 2009.
  4. Handa S. Aspergillosis. In: Ferri FF. Ferri's Clinical Advisor 2009. St. Louis, Mo.: Mosby; 2008. http://www.mdconsult.com/das/book/body/126486890-5/817668274/1701/64.html#4-u1.0-B978-0-323-04134-8..50004-5--subchapter59_1265. Accessed March 15, 2009.
  5. Rosenow EC (expert opinion). Mayo Clinic, Rochester, Minn. March 20, 2009.

DS00950

May 2, 2009

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