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Causes

By Mayo Clinic staff

It isn't clear why some people get asthma and others don't, but it's probably due to a combination of environmental and genetic (inherited) factors.

Asthma triggers
Exposure to various substances that trigger allergies (allergens) and irritants can trigger signs and symptoms of asthma. Asthma triggers are different from person to person and can include:

  • Airborne allergens, such as pollen, animal dander, mold, cockroaches and dust mites
  • Allergic reactions to some foods, such as peanuts or shellfish
  • Respiratory infections, such as the common cold
  • Physical activity (exercise-induced asthma)
  • Cold air
  • Air pollutants and irritants, such as smoke
  • Certain medications, including beta blockers, aspirin, ibuprofen (Advil, Motrin, others) and naproxen (Aleve)
  • Strong emotions and stress
  • Sulfites and preservatives added to some types of foods and beverages
  • Gastroesophageal reflux disease (GERD), a condition in which stomach acids back up into your throat
  • Menstrual cycle in some women
Risk factors Symptoms
References
  1. What is asthma? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/asthma/. Accessed March 14, 2012.
  2. McPhee SJ, et al. Current Medical Diagnosis & Treatment 2012. 51st ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/content.aspx?aID=2740. Accessed March 14, 2012.
  3. Parker MJ. Asthma. Otolaryngologic Clinics of North America. 2011;44:667.
  4. Asthma action plan. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/public/lung/asthma/asthma_actplan.htm. Accessed March 14, 2012.
  5. Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/content.aspx?aID=9127709. Accessed March 14, 2012.
  6. Asthma overview — What causes asthma? Asthma and Allergy Foundation of America. http://www.aafa.org/display.cfm?id=8&cont=6. Accessed March 13, 2012.
  7. Bjerg A. A strong synergism of low birth weight and prenatal smoking on asthma in schoolchildren. Pediatrics. 2011;127:e905.
  8. Ferri FF. Ferri's Clinical Advisor 2012: 5 Books in 1. Philadelphia, Pa. : Mosby Elsevier; 2011. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-0-323-05611-3..00010-0--sc0310&isbn=978-0-323-05611-3&sid=1283797418&uniqId=324341161-6#4-u1.0-B978-0-323-05611-3..00010-0--s6435. Accessed March 13, 2012.
  9. Asthma overview — Diagnosis. Asthma and Allergy Foundation of America. http://www.aafa.org/display.cfm?id=8&cont=7. Accessed March 13, 2012.
  10. Zafirlukast. Micromedex Healthcare Series. http://www.micromedex.com. Accessed March 14, 2012.
  11. Asthma overview — Treatment. Asthma and Allergy Foundation of America. http://www.aafa.org/display.cfm?id=8&cont=8. Accessed March 13, 2012.
  12. Hashimoto S, et al. Current treatment of severe asthma. Clinical and Experimental Allergy. In press. Accessed Mar. 14, 2012.
  13. Allergy overview — Treatment. Asthma and Allergy Foundation of America. http://www.aafa.org/display.cfm?id=9&cont=81. Accessed March 13, 2012.
  14. Mason RJ, et al. Murray and Nadel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4160-4710-0..00038-9--s0250&isbn=978-1-4160-4710-0&sid=1283802117&uniqId=324341161-7#4-u1.0-B978-1-4160-4710-0..00038-9--s0325. Accessed March 14, 2012.
  15. Indoor air quality and allergies. Asthma and Allergy Foundation of America. http://www.aafa.org/display.cfm?id=9&sub=18&cont=233. Accessed March 15, 2012.
  16. Bruton A, et al. The role of breathing training in asthma management. Current Opinion in Allergy and Clinical Immunology. 2011;11:53.
  17. Alternative therapies. Asthma and Allergy Foundation of America. http://www.aafa.org/display.cfm?id=8&sub=16&cont=40. March 14, 2012.
  18. Butterbur. Natural Medicines Comprehensive Database. http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=MAYO&s=nd&pt=100&id=649. Accessed March 15, 2012.
  19. Indian frankincense. Natural Medicines Comprehensive Database. http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=MAYO&s=nd&pt=100&id=63. Accessed March 15, 2012.
  20. Pycnogenol. Natural Medicines Comprehensive Database. http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=MAYO&s=nd&pt=100&id=1019. Accessed March 15, 2012.
  21. Fish oil. Natural Medicines Comprehensive Database. http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=MAYO&s=nd&pt=100&id=993. Accessed March 15, 2012.
  22. Li JT (expert opinion). Mayo Clinic, Rochester, Minn. March 22, 2012.
  23. Anderson CF (expert opinion). Mayo Clinic, Rochester, Minn. March 20, 2012.
DS00021 May 26, 2012

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