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By Mayo Clinic staffIf athlete's foot is severe or doesn't respond to over-the-counter medicine, you may need a prescription-strength topical medication (lotion, powder, spray or ointment) or an oral medication (pill, capsule or tablet). Many options are available, including:
- Terbinafine (Lamisil)
- Clotrimazole (Lotrimin)
- Miconazole (Monistat-Derm)
If your fungal infection is severe or doesn't respond to topical medicine, your doctor may give you a prescription oral medication. Oral medications include:
- Itraconazole (Sporanox)
- Fluconazole (Diflucan)
- Terbinafine (Lamisil)
Side effects from oral medications include gastrointestinal upset, rash and abnormal liver function. Taking other medications, such as antacid therapies for ulcer disease or gastroesophageal reflux disease (GERD), may interfere with the absorption of these drugs. Oral medications for athlete's foot may alter the effectiveness of warfarin, an anticoagulant drug that decreases the clotting ability of your blood.
Your doctor may prescribe an oral antibiotic if you have an accompanying bacterial infection. In addition, your doctor may recommend wet dressings, steroid ointments, compresses or vinegar soaks to help clear up blisters or soggy skin.
- Goldstein AO, et al. Dermatophyte (tinea) infections. http://www.uptodate.com/home/index.html. Accessed Sept. 22, 2008.
- Habif TP. Superficial fungal infections. In: Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 4th ed. Philadelphia, Pa.: Mosby Inc.; 2004. http://www.mdconsult.com/das/book/body/104355536-2/742469442/1195/81.html?printing=true. Accessed Sept. 22, 2008.
- Drugs@FDA. Food and Drug Administration. http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm. Accessed Sept. 22, 2008.
- Andrews MD, et al. Common tinea infections in children. American Family Physician. 2008;77(10):1415-1420.
- Gibson LE (expert opinion). Mayo Clinic Rochester, Minn. Oct. 16, 2008.