Atrial fibrillation

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Definition

By Mayo Clinic staff

Atrial fibrillation is an irregular and often rapid heart rate that commonly causes poor blood flow to the body. During atrial fibrillation, the heart's two upper chambers (the atria) beat chaotically and irregularly — out of coordination with the two lower chambers (the ventricles) of the heart. Atrial fibrillation symptoms include heart palpitations, shortness of breath and weakness.

Episodes of atrial fibrillation can come and go, or you may have chronic atrial fibrillation. Although atrial fibrillation itself usually isn't life-threatening, it is a serious medical condition that sometimes requires emergency treatment. It can lead to complications. Treatments for atrial fibrillation may include medications and other interventions to try to alter the heart's electrical system.

References
  1. Atrial fibrillation and flutter. Heart Rhythm Society. http://www.hrspatients.org/patients/heart_disorders/atrial_fibrillation/default.asp. Accessed Dec. 8, 2010.
  2. Atrial fibrillation. National Heart Lung and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/af/af_all.html. Accessed Dec. 8, 2010.
  3. Thomas MC, et al. Blood pressure control and the risk of incident atrial fibrillation. American Journal of Hypertension. 2008;21:1111.
  4. ACC/AHA/ESC Writing Committee members. 2006 guidelines for the management of patients with atrial fibrillation. Europace. 2006;8:651.
  5. Singer DE, et al. Antithrombotic therapy in atrial fibrillation: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133:546S.
  6. Connolly S, et al. Dabigatran versus warfarin in patients with atrial fibrillation. New England Journal of Medicine. 2009;361:1139.
  7. FDA approves Pradaxa to prevent stroke in people with atrial fibrillation. U.S. Food and Drug Administration. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm230241.htm. Accessed Dec. 8, 2010.
  8. Cardioversion. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/crv/crv_all.html. Accessed Dec. 8, 2010.
  9. Catheter ablation. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/ablation/ablation_all.html. Accessed Dec. 8, 2010.
  10. Cheng J, et al. Surgical approaches to prevent recurrent atrial fibrillation. http://www.uptodate.com/index. Accessed Dec. 8, 2010.
  11. Maze procedure for treatment of atrial fibrillation. University of Southern California Keck School of Medicine. http://www.cts.usc.edu/mazeprocedure.html. Accessed Dec. 1, 2010.
  12. Arrhythmia medications. American Heart Association. http://americanheart.org/presenter.jhtml?identifier=18. Accessed Nov. 30, 2010.
  13. Wann LS, et al. 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (updating the 2006 guideline): A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2010; In press. Accessed Dec. 20, 2010.
  14. FDA approves Xarelto to prevent stroke in people with common type of abnormal heart rhythm. U.S. Food and Drug Administration. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm278646.htm. Accessed Dec. 1, 2011.
DS00291 Feb. 3, 2012

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