Atrial fibrillation


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Definition

By Mayo Clinic staff

Heart-Healthy Living

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Atrial fibrillation is an irregular and often rapid heart rate that commonly causes poor blood flow to the body. During atrial fibrillation, the heart's two upper chambers (the atria) beat chaotically and irregularly — out of coordination with the two lower chambers (the ventricles) of the heart. Atrial fibrillation symptoms include heart palpitations, shortness of breath and weakness.

Episodes of atrial fibrillation can come and go, or you may have chronic atrial fibrillation. Although atrial fibrillation itself usually isn't life-threatening, it is a serious medical condition that sometimes requires emergency treatment. It can lead to complications. Treatments for atrial fibrillation may include medications and other interventions to try to alter the heart's electrical system.

References
  1. Atrial fibrillation (Afib). Heart Rhythm Society. http://www.hrsonline.org/Patient-Resources/Heart-Diseases-Disorders/Atrial-Fibrillation-AFib. Accessed Dec. 19, 2012.
  2. Atrial fibrillation. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/af/. Accessed Dec. 19, 2012.
  3. Verdecchia P, et al. Blood pressure and other determinants of new-onset atrial fibrillation in patients at high cardiovascular risk in the Ongoing Telmisartan Alone and in Combination With Ramipril Global Endpoint Trial/Telmisartan Randomized AssessmeNt Study in ACE intolerant subjects with cardiovascular disease studies. Journal of Hypertension. 2012;30:1004.
  4. Furie KL, et al. Oral antithrombotic agents for the prevention of stroke in nonvalvular atrial fibrillation: A science advisory for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2012;43:3442.
  5. Pradaxa (prescribing information). Ridgefield, Conn.: Boehringer Ingelheim Pharmaceuticals; 2012. https://www.pradaxa.com/pradaxa-prescribing-information.jsp. Accessed Dec. 19, 2012.
  6. Cardioversion. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/crv/. Accessed Dec. 19, 2012.
  7. Catheter ablation. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/ablation/. Accessed Dec. 19, 2012.
  8. Cheng J, et al. Surgical approaches to prevent recurrent atrial fibrillation. http://www.uptodate.com/home. Accessed Dec. 19, 2012.
  9. Kumar K. Antiarrhythmic drugs to maintain sinus rhythm in patients with atrial fibrillation: Recommendations. http://www.uptodate.com/home. Accessed Dec. 19, 2012.
  10. Wann LS, et al. 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (updating the 2006 guideline): A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2011;57:223.
  11. Xarelto (prescribing information). Titusville, N.J.: Jansen Pharmaceuticals; 2012. http://www.xareltorems.com/rems/xarelto-prescribing-information.html. Accessed Dec. 19, 2012.
  12. How the heart works. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/chd/heartworks.html. Accessed Dec. 19, 2012.
  13. FDA drug safety communication: Pradaxa (dabigatran etexilate mesylate) should not be used in patients with mechanical prosthetic heart valves. U.S. Food and Drug Administration. http://www.fda.gov/Drugs/DrugSafety/ucm332912.htm. Accessed Dec. 27, 2012.
DS00291 Feb. 8, 2013

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