Atrial fibrillation

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Complications

By Mayo Clinic staff

Heart-Healthy Living

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Sometimes atrial fibrillation can lead to the following complications:

  • Stroke. In atrial fibrillation, the chaotic rhythm may cause blood to pool in your heart's upper chambers (atria) and form clots. If a blood clot forms, it could dislodge from your heart and travel to your brain. There it might block blood flow, causing a stroke.

    The risk of stroke in atrial fibrillation depends on your age (you have a higher risk as you age) and on whether you have high blood pressure, diabetes, or a history of heart failure or previous stroke, and other factors. Certain medications, such as blood thinners, can greatly lower your risk of stroke or damage to other organs caused by blood clots.

  • Heart failure. Atrial fibrillation, especially if not controlled, may weaken the heart and lead to heart failure — a condition in which your heart can't circulate enough blood to meet your body's needs.
References
  1. Atrial fibrillation (Afib). Heart Rhythm Society. http://www.hrsonline.org/Patient-Resources/Heart-Diseases-Disorders/Atrial-Fibrillation-AFib. Accessed Dec. 19, 2012.
  2. Atrial fibrillation. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/af/. Accessed Dec. 19, 2012.
  3. Verdecchia P, et al. Blood pressure and other determinants of new-onset atrial fibrillation in patients at high cardiovascular risk in the Ongoing Telmisartan Alone and in Combination With Ramipril Global Endpoint Trial/Telmisartan Randomized AssessmeNt Study in ACE intolerant subjects with cardiovascular disease studies. Journal of Hypertension. 2012;30:1004.
  4. Furie KL, et al. Oral antithrombotic agents for the prevention of stroke in nonvalvular atrial fibrillation: A science advisory for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2012;43:3442.
  5. Pradaxa (prescribing information). Ridgefield, Conn.: Boehringer Ingelheim Pharmaceuticals; 2012. https://www.pradaxa.com/pradaxa-prescribing-information.jsp. Accessed Dec. 19, 2012.
  6. Cardioversion. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/crv/. Accessed Dec. 19, 2012.
  7. Catheter ablation. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/ablation/. Accessed Dec. 19, 2012.
  8. Cheng J, et al. Surgical approaches to prevent recurrent atrial fibrillation. http://www.uptodate.com/home. Accessed Dec. 19, 2012.
  9. Kumar K. Antiarrhythmic drugs to maintain sinus rhythm in patients with atrial fibrillation: Recommendations. http://www.uptodate.com/home. Accessed Dec. 19, 2012.
  10. Wann LS, et al. 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (updating the 2006 guideline): A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2011;57:223.
  11. Xarelto (prescribing information). Titusville, N.J.: Jansen Pharmaceuticals; 2012. http://www.xareltorems.com/rems/xarelto-prescribing-information.html. Accessed Dec. 19, 2012.
  12. How the heart works. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/chd/heartworks.html. Accessed Dec. 19, 2012.
  13. FDA drug safety communication: Pradaxa (dabigatran etexilate mesylate) should not be used in patients with mechanical prosthetic heart valves. U.S. Food and Drug Administration. http://www.fda.gov/Drugs/DrugSafety/ucm332912.htm. Accessed Dec. 27, 2012.
DS00291 Feb. 8, 2013

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