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Definition

By Mayo Clinic staff

As with any type of depression, atypical depression can make you feel blue and keep you from enjoying life. When you have atypical depression, a particular pattern of signs and symptoms tends to occur. You may feel hungry and gain weight. You may sleep a lot, and your arms and legs may feel heavy. Many people who have atypical depression have a hard time maintaining relationships and are especially afraid of rejection by others.

Atypical depression often starts in the teenage years and is more common in women than in men. Despite the name, atypical depression isn't uncommon or unusual. As with other forms of depression, treatment for atypical depression includes medications, psychological counseling (psychotherapy) and lifestyle changes.

References
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  2. Atypical features specifier. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Arlington, Va.: American Psychiatric Association; 2000. http://www.psychiatryonline.com. Accessed April 13, 2010.
  3. Stewart JW, et al. DSM-IV Depression with atypical features: Is it valid? Neuropsychopharmacology. 2009;34:2625.
  4. Pae C, et al. Atypical depression: A comprehensive review. CNS Drugs. 2009;2:1023.
  5. Depression. National Institute of Mental Health. http://www.nimh.nih.gov/health/publications/depression/index.shtml. Accessed April 13, 2010.
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  8. Katon W, et al. Initial treatment of depression in adults. http://www.uptodate.com/home/index.html. Accessed April 13, 2010.
  9. Kung S (expert opinion). Mayo Clinic, Rochester, Minn. April 26, 2010.
  10. Martinez M, et al. Psychopharmacology. In: Hales RE. Textbook of Psychiatry. Arlington, Va.: American Psychiatric Publishing; 2008. http://www.psychiatryonline.com/content.aspx?aID=320111. Accessed April 13, 2010.
  11. van der Watt G, et al. Complementary and alternative medicine in the treatment of anxiety and depression. Current Opinion in Psychiatry. 2008;2:37.
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DS01181 May 20, 2010

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