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Symptoms

By Mayo Clinic staff

Depression of any kind can cause:

  • Feelings of sadness, emptiness or feeling tearful
  • Loss of interest or pleasure in normal activities

In addition to standard symptoms of depression, atypical depression symptoms also include:

  • Increased appetite
  • Unintentional weight gain
  • Increased desire to sleep
  • Heavy, leaden feeling in the arms and legs
  • Sensitivity to rejection or criticism that interferes with your social life or job
  • Relationship conflicts
  • Trouble maintaining long-lasting relationships
  • Fear of rejection that leads to avoiding relationships
  • Having depression that temporarily lifts with good news or positive events but returns later

When to see a doctor
If you feel depressed, make an appointment to see your doctor as soon as you can. Depression may get worse if it isn't treated. Untreated depression can lead to other mental and physical health problems or problems in other areas of your life. Feelings of depression can also lead to suicide.

If you're reluctant to seek treatment, talk to a friend or loved one, a health care professional, a faith leader, or someone else you trust.

If you have suicidal thoughts
If you or someone you know is having suicidal thoughts, get help right away. Here are some steps you can take:

  • Contact a family member or friend.
  • Seek help from your doctor, a mental health provider or another health care professional.
  • Call a suicide hot line number — in the United States, you can reach the toll-free, 24-hour hot line of the National Suicide Prevention Lifeline at 800-273-8255 to talk to a trained counselor.
  • Contact a minister, a spiritual leader or someone in your faith community.

When to get emergency help
If you think you may hurt yourself or attempt suicide, call 911 or your local emergency number immediately. If you have a loved one who has harmed himself or herself, or is seriously considering doing so, make sure someone stays with that person. Take him or her to the hospital or call for emergency help.

References
  1. Depressive disorders. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Arlington, Va.: American Psychiatric Association; 2000. http://www.psychiatryonline.com. Accessed April 13, 2010.
  2. Atypical features specifier. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Arlington, Va.: American Psychiatric Association; 2000. http://www.psychiatryonline.com. Accessed April 13, 2010.
  3. Stewart JW, et al. DSM-IV Depression with atypical features: Is it valid? Neuropsychopharmacology. 2009;34:2625.
  4. Pae C, et al. Atypical depression: A comprehensive review. CNS Drugs. 2009;2:1023.
  5. Depression. National Institute of Mental Health. http://www.nimh.nih.gov/health/publications/depression/index.shtml. Accessed April 13, 2010.
  6. Lyness JM. Depression: Epidemiology and pathogenesis. http://www.uptodate.com/home/index.html. Accessed April 13, 2010.
  7. Loosen PT, et al. Mood disorders. In: Ebert MH, et al. Current Diagnosis and Treatment: Psychiatry. 2nd ed. New York, N.Y.: McGraw Hill; 2008. http://www.accessmedicine.com/content.aspx?aid=3285019. Accessed April 13, 2010.
  8. Katon W, et al. Initial treatment of depression in adults. http://www.uptodate.com/home/index.html. Accessed April 13, 2010.
  9. Kung S (expert opinion). Mayo Clinic, Rochester, Minn. April 26, 2010.
  10. Martinez M, et al. Psychopharmacology. In: Hales RE. Textbook of Psychiatry. Arlington, Va.: American Psychiatric Publishing; 2008. http://www.psychiatryonline.com/content.aspx?aID=320111. Accessed April 13, 2010.
  11. van der Watt G, et al. Complementary and alternative medicine in the treatment of anxiety and depression. Current Opinion in Psychiatry. 2008;2:37.
  12. Mischoulon D. Update and critique of natural remedies as antidepressant treatments. Obstetrics & Gynecology Clinics of North America. 2009;36:789.
  13. Wahner-Roedler D. Treating 20 common conditions. In: Bauer B. Mayo Clinic Book of Alternative Medicine. 2nd ed. New York, N.Y.: Time Inc.; 2010:167.
DS01181 May 20, 2010

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