Autoimmune hepatitis

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Risk factors

By Mayo Clinic staff

Factors that may increase your risk of autoimmune hepatitis include:

  • Being female. Although both men and women can develop autoimmune hepatitis, the disease is far more common in women.
  • Age. Type 1 autoimmune hepatitis can occur at any age. Type 2 primarily affects young girls.
  • A history of certain infections. Autoimmune hepatitis may develop after a bacterial or viral infection.
  • Use of certain medications. Certain medications, such as the antibiotic minocycline and the cholesterol medication atorvastatin (Lipitor) have been linked to autoimmune hepatitis.
  • Heredity. Evidence suggests that a predisposition to autoimmune hepatitis may run in families.
References
  1. Autoimmune hepatitis. National Institute for Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/autoimmunehep/index.htm. Accessed Jan. 15, 2010.
  2. Promrat K, et al. Hepatitis, autoimmune. In: Ferri FF. Ferri's Clinical Advisor 2010. Philadelphia, Pa.: Mosby; 2010. http://www.mdconsult.com/das/book/body/178515191-4/0/2088/0.html. Accessed Jan. 15, 2010.
  3. Czaja AJ. Autoimmune hepatitis. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2006. http://www.mdconsult.com/das/book/body/178515191-4/0/1389/0.html. Accessed Jan. 15, 2010.
  4. Luxon BA. Diagnosis and treatment of autoimmune hepatitis. Gastroenterology Clinics of North America. 2008;37:461.
  5. Teufel A, et al. Concurrent autoimmune diseases in patients with autoimmune hepatitis. Journal of Clinical Gastroenterology. In press. Accessed Jan. 27, 2010.
DS00676 Feb. 27, 2010

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