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Risk factors
By Mayo Clinic staffFactors that may increase your risk of autonomic neuropathy include:
- Diabetes. Diabetes, especially poorly controlled diabetes, increases your risk of developing nerve damage, including autonomic neuropathy. The risk is greatest for people who've had the disease for more than 25 years and have difficulty controlling their blood sugar. Additionally, people with diabetes who are overweight or have high blood pressure or high cholesterol have a higher risk of autonomic neuropathy.
- Alcoholism. People who abuse alcohol have a higher risk of nerve damage.
- Other diseases. A number of other diseases also increase your risk of autonomic neuropathy, including amyloidosis, cancer, systemic lupus erythematosus and other autoimmune diseases, HIV/AIDS, Parkinson's disease, and botulism.
References
- Freeman R. Autonomic peripheral neuropathy. Neurologic Clinics. 2007;25:277.
- Stevens MJ. Diabetic autonomic neuropathy. http://www.uptodate.com/home/index.html. Accessed Jan. 29, 2010.
- Autonomic neuropathy. American Diabetes Association. http://www.diabetes.org/living-with-diabetes/complications/neuropathy/autonomic-neuropathy.html. Accessed Feb. 22, 2010.
- Masharani U, et al. Pancreatic hormones and diabetes mellitus. In: Gardner DG, et al. Greenspan's Basic and Clinical Endocrinology. 8th ed. New York, N.Y.: McGraw-Hill Medical; 2007. http://www.accessmedicine.com/content.aspx?aID=2633151. Accessed Feb. 22, 2010.
- Diabetic neuropathies: The nerve damage of diabetes. National Institute of Diabetes and Digestive and Kidney Diseases. http://diabetes.niddk.nih.gov/DM/pubs/neuropathies/. Accessed Feb. 21, 2010.
- Boulton AJM, et al. Diabetic neuropathies: A statement from the American Diabetes Association. Diabetes Care. 2005;28:956.
- Disorders of the autonomic nervous system. In: Fauci AS, et al. Harrison's Principles of Internal Medicine. 17th ed. New York, N.Y.: McGraw-Hill Medical; 2008. http://www.accessmedicine.com/content.aspx?aID=2906166. Accessed Feb. 22, 2010.
- Vink AI. Diabetic autonomic neuropathy. Diabetes Care. 2003;26:1553.
- Autonomic nervous system. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec16/ch208/ch208a.html. Accessed Feb. 22, 2010.
- Ma J, et al. Diabetic gastroparesis: Diagnosis and management. Drugs. 2009;69:971.
- Bethanechol (prescribing information). Minneapolis, Minn.: Upsher-Smith Laboratories, Inc.; 2005. http://www.upsher-smith.com/PDFs/bethanechol.pdf. Accessed Feb. 22, 2010.
- Robinul and Robinul Forte (prescribing information). Atlanta, Ga.: Sciele Pharma, Inc.; 2006. http://www.shionogipharma.com/PI/Robinul%20PI.pdf. Accessed Feb. 22, 2010.
- Bansal V, et al. Diabetic neuropathy. Post Graduate Medical Journal. 2006;82:95.
- Sandroni P (expert opinion). Mayo Clinic, Rochester, Minn. March 1, 2010.
- Detrol (prescribing information). New York, N.Y.: Pharmacia and Upjohn; 2009. http://www.pfizer.com/files/products/uspi_detrol_la.pdf. Accessed March 8, 2010.
- Ditrol (prescribing information). Raritan, N.J.: Ortho McNeil Pharmaceuticals; 2008. http://www.ortho-mcneilpharmaceutical.com/sites/default/files/shared/pi/Lg%20Ditropan%20PI.pdf#zoom=100. Accessed March 8, 2010.
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