Risk factorsBy Mayo Clinic staff
Factors that increase your risk of Barrett's esophagus include:
- Chronic heartburn and acid reflux. Having these symptoms of gastroesophageal reflux disease (GERD) for more than 10 years can increase the risk of Barrett's esophagus. Stomach acid that backs up into your esophagus if you have GERD can damage the esophageal tissue, causing the changes that signal Barrett's esophagus.
- Being a man. Men are more likely to develop Barrett's esophagus.
- Being white. White people have a greater risk of the disease than do people of other races.
- Being an older adult. Barrett's esophagus is more common in older adults, but it can occur at any age.
- Spechler SJ, et al. Barrett's esophagus. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229935664-2192. Accessed March 25, 2011.
- Updated guidelines 2008 for the diagnosis, surveillance and therapy of Barrett's esophagus. Bethesda, Md.: American College of Gastroenterology. http://www.acg.gi.org/physicians/guidelines/BarrettsEsophagus08.pdf. Accessed March 25, 2011.
- Azodo IA, et al. Barrett's esophagus. American College of Gastroenterology. http://www.acg.gi.org/patients/gihealth/barretts.asp. Accessed March 25, 2011.
- Spechler SJ, et al. American Gastroenterological Association medical position statement on the management of Barrett's esophagus. Gastroenterology. 2011;140:1084.
- Barrett's esophagus. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/barretts/index.htm. Accessed March 25, 2011.
- Crockett SD, et al. Health-related quality of life in patients with Barrett's esophagus: A systematic review. Clinical Gastroenterology and Hepatology. 2009;7:613.
- Heartburn, gastroesophageal reflux (GER), and gastroesophageal reflux disease (GERD). National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/gerd/index.htm. Accessed March 28, 2011.
- Greenwald BD, et al. Cryotherapy for Barrett's esophagus and esophageal cancer. Current Opinion in Gastroenterology. In press. Accessed May 23, 2011.