Behcet's disease

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Causes

By Mayo Clinic staff

Doctors don't know what causes Behcet's disease. Many believe Behcet's disease is an autoimmune disorder in which your body's defense system — your immune system — turns on itself. Rather than attack foreign invaders, such as bacteria and viruses, your immune system attacks healthy cells in your body.

Behcet's disease is likely caused by a combination of genetic and environmental factors. Some researchers believe a virus or bacterium may trigger Behcet's disease in people who have a certain genetic background. Other possible triggers that could set off the immune system could include chemicals or heavy metals.

References
  1. Smith EL. Clinical manifestations and diagnosis of Behcet's disease. http://www.uptodate.com/home/index.html. Accessed Aug. 4, 2008.
  2. Questions and answers about Behcet's disease. National Institute of Arthritis and Musculoskeletal and Skin Diseases. www.niams.nih.gov/hi/topics/behcets/behcets.htm. Accessed Aug. 4, 2008.
  3. Smith EL, et al. Pathogenesis of Behcet's disease. http://www.uptodate.com/home/index.html. Accessed Aug. 4, 2008.
  4. Smith EL, et al. Treatment of Behcet's disease. http://www.uptodate.com/home/index.html. Accessed Aug. 4, 2008.

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Oct. 30, 2008

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