Risk factors
By Mayo Clinic staffFactors that may increase your risk of Behcet's include:
- Age. Behcet's disease commonly affects men and women in their 20s and 30s, though children and older adults also can develop the condition.
- Location. Although the disease occurs worldwide, people from countries in the Middle East and Far East, including Turkey, Iran, Japan and China, are more likely to develop Behcet's.
- Sex. While Behcet's disease occurs in both men and women, the disease is usually more severe in men.
- Genes. Having certain genes is associated with a higher risk of developing Behcet's.
References
- Saadoun D, et al. Behcet's disease. Orphanet Journal of Rare Diseases. 2012;7:1.
- Questions and answers about Behcet's disease. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Behcets_Disease/default.asp. Accessed Nov. 15, 2012.
- Mendes D, et al. Behcet's disease — A contemporary review. Journal of Autoimmunity. 2009;32:178.
- Ambrose NL, et al. Differential diagnosis and management of Behcet syndrome. Nature Reviews Rheumatology. In press. Accessed Jan. 13, 2013.
- Okada AA, et al. Multicenter study of infliximab for refractory uveoretinitis in Behcet disease. Archives of Ophthalmology. 2012;130:592.
- Arida A, et al. Anti-TNF agents for Behcet's disease: Analysis of published data on 369 patients. Seminars in Arthritis and Rheumatism. 2011;41:61.
- Benitah NR, et al. The use of biologic agents in the treatment of ocular manifestations of Behcet's disease. Seminars in Ophthalmology. 2011;26:295.


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