Behcet's disease

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Risk factors

By Mayo Clinic staff

Factors that may increase your risk of Behcet's include:

  • Age. Behcet's disease commonly affects men and women in their 20s and 30s, though children and older adults also can develop the condition.
  • Location. Although the disease occurs worldwide, people from countries in the Middle East and Far East, including Turkey, Iran, Japan and China, are more likely to develop Behcet's.
  • Sex. While Behcet's disease occurs in both men and women, the disease is usually more severe in men.
  • Genes. Having certain genes is associated with a higher risk of developing Behcet's.
References
  1. Saadoun D, et al. Behcet's disease. Orphanet Journal of Rare Diseases. 2012;7:1.
  2. Questions and answers about Behcet's disease. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Behcets_Disease/default.asp. Accessed Nov. 15, 2012.
  3. Mendes D, et al. Behcet's disease — A contemporary review. Journal of Autoimmunity. 2009;32:178.
  4. Ambrose NL, et al. Differential diagnosis and management of Behcet syndrome. Nature Reviews Rheumatology. In press. Accessed Jan. 13, 2013.
  5. Okada AA, et al. Multicenter study of infliximab for refractory uveoretinitis in Behcet disease. Archives of Ophthalmology. 2012;130:592.
  6. Arida A, et al. Anti-TNF agents for Behcet's disease: Analysis of published data on 369 patients. Seminars in Arthritis and Rheumatism. 2011;41:61.
  7. Benitah NR, et al. The use of biologic agents in the treatment of ocular manifestations of Behcet's disease. Seminars in Ophthalmology. 2011;26:295.
DS00822 March 8, 2013

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