IgA nephropathy (Berger's disease)

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Definition

IgA nephropathy — also called Berger's disease — is a common kidney disease that occurs when an antibody called IgA lodges in your kidneys. This hampers your kidneys' ability to filter waste and excess water from your blood. Over time, IgA nephropathy can lead to blood and protein in your urine, high blood pressure, and swollen hands and feet.

IgA nephropathy usually progresses slowly over many years, and although some people eventually achieve complete remission, others develop end-stage kidney failure. No cure exists for IgA nephropathy, but certain medications can slow its course.

Keeping your blood pressure under control, limiting protein in your diet and reducing your cholesterol levels also may help keep IgA nephropathy in check.

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Symptoms