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  • With Mayo Clinic urologist

    Erik Castle, M.D.

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Mayo Clinic Health Manager

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Question

Chronic bladder infection: Is there a cure?

I have had a chronic bladder infection for the past four years. My doctor just keeps giving me antibiotics, but the infection keeps coming back. What can I do?

Answer

from Erik Castle, M.D.

You're not alone. Various studies have found that between 27 and 50 percent of otherwise healthy women experience at least one recurrent bladder infection (cystitis) within a year of the first infection.

There can be several causes of chronic bladder infections, such as:

  • Kidney or bladder stones
  • Bacteria entering the urethra during sexual intercourse
  • Altered estrogen levels during menopause
  • Abnormal urinary tract shape or function
  • Genetic predisposition

In general, women who have two or more culture-documented bladder infections in a six-month period should be evaluated by a urologist to determine the underlying cause. The evaluation may include:

  • Urine culture of a sample obtained with a catheter
  • Cystoscopy — looking into the bladder with a lighted scope
  • Computerized tomography (CT) scan 

Treatment is directed at the underlying cause, when possible. If no source of infection is found, lifestyle modifications combined with vaginal estrogen replacement is all you may need. Lifestyle modifications that may reduce your risk of bladder infection include:

  • Drinking plenty of liquids, especially water
  • Drinking cranberry juice, though studies with promising results had limitations
  • Urinating frequently
  • Wiping from front to back after a bowel movement
  • Taking showers rather than tub baths
  • Gently washing the skin around your vagina and anus daily using a mild soap and plenty of water
  • Using forms of birth control other than a diaphragm and spermicides
  • Emptying your bladder as soon as possible after intercourse
  • Avoiding deodorant sprays or scented feminine products in the genital area

Otherwise, long-term, low-dose, preventive antibiotics is the only treatment option. In such cases, you may need to take antibiotics for as long as six months to two years.

Next question
Bladder infection in men: What are the symptoms?
References
  1. Hooten TM, et al. Recurrent urinary tract infection in women. http://www.uptodate.com/home/index.html. Accessed Sept. 9, 2009.
  2. Rahn DD. Urinary tract infections: Contemporary management. Urologic Nursing. 2008;28:33.
  3. Sen A. Recurrent cystitis in non-pregnant women. BMJ Clinical Evidence. 2008;7:801.
  4. Castle EP (expert opinion). Mayo Clinic, Scottsdale, Ariz. Sept. 9, 2009.

AN01683

Oct. 1, 2009

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