- With Mayo Clinic emeritus hypertension specialist
Sheldon G. Sheps, M.D.
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Sheldon G. Sheps, M.D.
Sheldon G. Sheps, M.D.
Dr. Sheldon Sheps, emeritus professor of medicine and former chair of the Hypertension Division in the Department of Medicine at Mayo Clinic, has been with Mayo Clinic since 1960.
Dr. Sheps, a Winnipeg, Manitoba, native, is board certified in internal medicine and specializes in hypertension and peripheral vascular diseases. He developed a multidisciplinary approach with specially trained nurses, dietitians, technicians and educators to help form a team approach to the treatment of patients with abnormal blood pressure.
"I have always believed in involving the patient and family in their health care," he says. "I have asked for their understanding of the illness and issues and for participation in decisions. The Web is a natural extension of that, and now many more people can be informed."
Dr. Sheps chaired the sixth working group, and participated in the fourth, fifth and seventh groups, that developed the then-latest guidelines for hypertension under the auspices of the National Heart, Lung and Blood Institute (NHLBI). He helped write the latest American Heart Association (AHA) report on blood pressure measurement. He chaired an AHA group that produced an online accreditation for blood pressure measurement for health professionals. He has co-authored books, newsletters, CD-ROMs and other Mayo Clinic health information material and joined Mayo Clinic's Web team in 1998. He was medical editor-in-chief of both editions of the "Mayo Clinic on High Blood Pressure" book; the last edition was published in 2003. He was also medical editor-in-chief of "Mayo Clinic 5 Steps to Controlling High Blood Pressure,'' published in 2008.
He was section editor for each of the first three editions of "Hypertension Primer" for the American Heart Association.
Dr. Sheps was also chairman of the Science Base Subcommittee, National High Blood Pressure Education Program, and was a consultant to the Hypertension Initiative of the World Health Organization. In 1997, he was honored with the Individual Achievement Award on the 25th anniversary of the National High Blood Pressure Education Program of NHLBI. In 2009, he was honored as a Distinguished Mayo Alumnus.
Definition (3)
- Isolated systolic hypertension: A health concern?
- Blood pressure: Is it affected by weather?
- White-coat hypertension: When blood pressure rises at the doctor's office
Risk factors (2)
- Alcohol: Does it affect blood pressure?
- Menopause and high blood pressure: What's the connection?
Symptoms (1)
- Pulse pressure: An indicator of heart health?
Causes (5)
- Blood pressure: Does it have a daily pattern?
- Caffeine: How does it affect blood pressure?
- Blood pressure readings: Why higher at home?
- see all in Causes
Complications (1)
- Hypertensive crisis: What are the symptoms?
Treatments and drugs (5)
- Blood pressure medications: Can they raise my triglycerides?
- Calcium supplements: Do they interfere with blood pressure drugs?
- Diuretics: A cause of low potassium?
- see all in Treatments and drugs
Lifestyle and home remedies (9)
- Water softeners: How much sodium do they add?
- Weightlifting: Bad for your blood pressure?
- Blood pressure medication: Still necessary if I lose weight?
- see all in Lifestyle and home remedies
Alternative medicine (1)
- L-arginine: Does it lower blood pressure?
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Question
Blood pressure medications: Can they raise my triglycerides?
Can some blood pressure medications cause an increase in triglyceride levels?
Answer
from Sheldon G. Sheps, M.D.
Yes, some blood pressure medications can affect cholesterol levels, including triglycerides.
Beta blockers — most notably the older ones such as propranolol, atenolol and metoprolol — can slightly increase triglyceride levels and decrease high-density lipoprotein (HDL, or "good") cholesterol. Typically this occurs in people who are more predisposed to or who already have metabolic syndrome — a cluster of conditions that includes high blood pressure, high blood sugar, excess fat around the abdomen and high cholesterol. Newer beta blockers such as carvedilol and nebivolol are less often associated with these changes.
Thiazide diuretics in higher doses also can slightly increase triglycerides as well as total cholesterol. Some observational studies have linked such changes with an increase in cardiovascular events, such as heart attacks. However, controlled trials haven't corroborated this, and in fact, have found a reduction in cardiovascular events with diuretics. Still, meta-analyses of the older beta blocker drugs conclude that these agents should not be initial drugs of choice in the treatment of high blood pressure except in specific instances such as to prevent recurrent coronary artery disease, to manage heart failure and to treat certain arrhythmias.
Before making any changes in your drug therapy, discuss this with your doctor.
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