Bone marrow biopsy and aspiration

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Risks

By Mayo Clinic staff

Bone marrow exams are safe procedures. Complications are rare but can include:

  • Excessive bleeding, particularly in people with a low platelet count
  • Infection, especially in people with weakened immune systems
  • Long-lasting discomfort at the biopsy site
  • Penetration of the breastbone (sternum) during sternal aspirations, which can cause heart or lung problems
  • Complications related to sedation, such as an allergic reaction, nausea or irregular heartbeats
References
  1. What are bone marrow tests? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/bmt. Accessed Nov. 4, 2011.
  2. Ryan DH. Examination of the marrow. In: Lichtman MA, et al. Williams Hematology. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2010. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=69. Accessed Nov. 4, 2011.
  3. Gomella LG, et al. Bedside procedures (bone marrow aspiration and biopsy). Clinician's Pocket Reference. 11th ed. New York, N.Y.: The McGraw-Hill Companies; 2007. http://www.accessmedicine.com/content.aspx?aID=2694363. Accessed Nov. 4, 2011.
  4. Mesa RA (expert opinion). Mayo Clinic, Scottsdale, Ariz. Nov. 14, 2011.
MY00305 Dec. 13, 2011

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