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Botox injections: Can they relieve arthritis pain?By Mayo Clinic staff
Original Article: http://www.mayoclinic.com/health/botox-injections/AN01520
- With Mayo Clinic rheumatologist
April Chang-Miller, M.D.read biographyclose window
April Chang-Miller, M.D.April Chang-Miller, M.D.
Dr. April Chang-Miller is board certified in internal medicine and rheumatology and is a consultant in the Division of Rheumatology at Mayo Clinic in Arizona.
Dr. Chang-Miller's primary field is rheumatology with special interests in inflammatory joint diseases called seronegative spondyloarthropathies, such as ankylosing spondylitis and psoriatic arthritis. She also cares for patients with rheumatoid arthritis and polymyalgia rheumatica.
The New York City native is a graduate of the Yale School of Medicine. Dr. Chang-Miller joined the Mayo Clinic staff in Rochester, Minn., in 1991, and in 2002 she relocated to Mayo Clinic in Arizona. She is a fellow in the American College of Rheumatology and has been on the board of directors of the Arthritis Foundation North Central Chapter.
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Botox injections: Can they relieve arthritis pain?
Can Botox injections relieve arthritis pain?
from April Chang-Miller, M.D.
In early studies, Botox injections appear to reduce arthritis pain in the shoulder, knee and hip. These results are promising, but they fall short of proving that Botox injections are an effective treatment for arthritis pain.
Botox is the brand name for onabotulinumtoxinA — the pharmaceutical form of botulinum toxin type A. This toxin is produced by the bacterium that causes the food poisoning botulism. When injected in small doses into specific muscles, Botox blocks the chemical signals that cause muscles to contract.
So far, participants in various studies have reported improvement in arthritis pain and function after Botox injections. There's much left to learn about the possible role of Botox injections in arthritis treatment, however. While research continues, proven treatment options — such as exercise, weight loss and medication — remain the focus of most arthritis treatment plans.Next question
After a flood, are food and medicine safe to use?
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- Marchini C, et al. Efficacy of botulinum toxin type A treatment of functional impairment of degenerative hip joint: Preliminary results. Journal of Rehabilitation Medicine. 2010;42:691.
- Boon AJ, et al. Efficacy of intra-articular botulinum toxin type A in painful knee osteoarthritis: A pilot study. PM&R. 2010;2:268.
- Singh JA, et al. Intra-articular botulinum toxin A for refractory shoulder pain: A randomized, double-blinded, placebo-controlled trial. Translational Research. 2009;153:205.
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- Botox (prescribing information). Irvine, Calif.: Allergan Inc.; 2009. http://www.allergan.com/assets/pdf/botox_cosmetic_pi.pdf. Accessed Jan. 14, 2011.