Why it's doneBy Mayo Clinic staff
Botulinum toxin injections block certain chemical signals from nerves, mostly signals that cause muscles to contract. The most common use of these injections is to temporarily relax the facial muscles that underlie and cause wrinkles, such as:
- Frown lines between the eyebrows
- Crow's-feet, the lines that fan out from the corners of the eyes
- Forehead furrows, the horizontal lines that form when you raise your eyebrows
In addition to these cosmetic procedures, which simply improve your appearance, botulinum toxin injections have also been used to treat conditions that affect how your body functions. Examples include:
- Cervical dystonia. In this painful condition, your neck muscles contract involuntarily, causing your head to twist or turn into an uncomfortable position.
- Lazy eye. The most common cause of lazy eye is an imbalance in the muscles responsible for positioning the eye. This can result in crossed eyes.
- Muscle contractures. Some neurological conditions, such as cerebral palsy, can cause your limbs to pull in toward your center. In some cases, these contracted muscles can be relaxed with botulinum toxin injections.
- Hyperhidrosis. In this condition, excessive sweating occurs even when the temperature isn't hot and you're not exercising. In some people, the sweat literally drips off their hands.
- Chronic migraine. If you experience migraines more than 15 days a month, botulinum toxin injections may help reduce headache frequency.
- Bladder dysfunction. Botulinum toxin injections can also help reduce urinary incontinence caused by an overactive bladder.
- Carruthers J, et al. Overview of botulinum toxin for cosmetic injections. http://www.uptodate.com/index. Accessed Dec. 14, 2012.
- Botox medication guide. Food and Drug Administration. http://www.fda.gov/downloads/Drugs/DrugSafety/UCM176360.pdf. Accessed Dec. 14, 2012.
- AskMayoExpert. Botulinum toxin. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
- OnabotulinumtoxinA (botulinum toxin type A, Botox): Drug information. http://www.uptodate.com/index. Accessed Dec. 14, 2012.
- FDA approves Botox to treat overactive bladder. U.S. Food and Drug Administration. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm336101.htm. Jan. 18, 2013.
- OnabotulinumtoxinA (marketed as Botox/Botox Cosmetic), AbobotulinumtoxinA (marketed as Dysport) and RimabotulinumtoxinB (marketed as Myobloc) information. U.S. Food and Drug Administration. FDA boxed warning alert: August 2009. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/ucm174949.htm. Accessed Dec. 17, 2012.
- Barbara Woodward Lips Patient Education Center. Botulinum toxin treatment. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
- Barbara Woodward Lips Patient Education Center. Managing pain for your child's Botox injection. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.